Kim, D. N.; Gront, D.; Sanbonmatsu, K. Y. Practical Considerations for Atomistic Structure Modeling with Cryo-EM Maps. Journal of chemical information and modeling, 2020, 60, 2436-2442
We describe common approaches to atomistic structure modeling with single particle analysis derived cryo-EM maps. Several strategies for atomistic model building and atomistic model fitting methods are discussed, including selection criteria and implementation procedures. In covering basic concepts and caveats, this short perspective aims to help facilitate active discussion between scientists at different levels with diverse backgrounds.