Difference between revisions of "2011Vonesch Wavelets"
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+ | Vonesch C.; Wang L.; Shkolnisky Y. & A. Singer. Fast wavelet-based single-particle reconstruction in cryo-EM. 8th IEEE International Symposium on Biomedical Imaging (ISBI’11), March 30 – April 2, 2011. | ||
== Abstract == | == Abstract == | ||
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== Related software == | == Related software == | ||
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+ | ASPIRE | ||
== Related methods == | == Related methods == | ||
== Comments == | == Comments == |
Latest revision as of 20:09, 16 July 2014
Citation
Vonesch C.; Wang L.; Shkolnisky Y. & A. Singer. Fast wavelet-based single-particle reconstruction in cryo-EM. 8th IEEE International Symposium on Biomedical Imaging (ISBI’11), March 30 – April 2, 2011.
Abstract
This paper presents a novel algorithm for the 3D tomographic inversion problem that arises in single-particle electron cryomicroscopy (Cryo-EM). It is based on two key components: 1) a variational formulation that promotes sparsity in the wavelet domain and 2) the Toeplitz structure of the combined projection/back-projection operator. The first idea has proven to be very effective for the recovery of piecewise-smooth signals, which is confirmed by our numerical experiments. The second idea allows for a computationally efficient implementation of the reconstruction procedure, using only one circulant convolution per iteration.
Keywords
L1 wavelet regularization, promoting sparsity, Landweber thresholding, Toeplitz.
Links
http://www.ncbi.nlm.nih.gov/pubmed/22536462
Related software
ASPIRE