View source for 2023Geva AbInitio

== Citation ==

A. S. Geva and Y. Shkolnisky, “A common lines approach for ab initio modeling of molecules with tetrahedral and octahedral symmetry,” SIAM J. on Imaging Sciences, vol. 16, no. 4, pp. 1978–2014, 2023.

== Abstract ==

A main task in cryo-electron microscopy single particle reconstruction is to nd
a three-dimensional model of a molecule given a set of its randomly oriented and
positioned noisy projection-images. In this work, we propose an algorithm for ab-initio
reconstruction for molecules with tetrahedral or octahedral symmetry. The algorithm
exploits the multiple common lines between each pair of projection-images as well as
self common lines within each image. It is robust to noise in the input images as it
integrates the information from all images at once. The eciency of the proposed
algorithm is demonstrated using experimental cryo-electron microscopy data.

== Keywords ==

== Links ==

https://epubs.siam.org/doi/abs/10.1137/22M150383X

== Related software ==

== Related methods ==

== Comments ==