https://3demmethods.i2pc.es/index.php?action=history&feed=atom&title=2006Sorzano_Review 2026-05-24T20:40:45Z Revision history for this page on the wiki MediaWiki 1.44.2 https://3demmethods.i2pc.es/index.php?title=2006Sorzano_Review&diff=1489&oldid=prev 2009-04-01T12:47:50Z

<p></p> <p><b>New page</b></p><div>== Citation ==<br /> <br /> Sorzano, C. O. S.; Marabini, R.; Pascual-Montano, A.; Scheres, S. H. W. &amp; Carazo, J. M. Optimization problems in electron microscopy of single particles Annals of Operations Research, 2006<br /> <br /> [http://scholar.google.com/scholar?hl=en&amp;lr=&amp;newwindow=1&amp;cites=12811490209335773142 Cited by]<br /> <br /> == Abstract ==<br /> <br /> Electron Microscopy is a valuable tool for the elucidation of the three-dimensional<br /> structure of macromolecular complexes. Knowledge about the macromolecular structure provides<br /> important information about its function and how it is carried out. This work addresses<br /> the issue of three-dimensional reconstruction of biological macromolecules from electron<br /> microscopy images. In particular, it focuses on a methodology known as “single-particles”<br /> and makes a thorough review of all those steps that can be expressed as an optimization<br /> problem. In spite of important advances in recent years, there are still unresolved challenges<br /> in the field that offer an excellent testbed for new and more powerful optimization techniques.<br /> <br /> == Keywords ==<br /> <br /> Optimization problems<br /> <br /> == Links ==<br /> <br /> Article http://www.springerlink.com/index/3146343106370685.pdf<br /> <br /> == Related software ==<br /> <br /> == Related methods ==<br /> <br /> == Comments ==</div>

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