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	<title>2007Fernandez autAND - Revision history</title>
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		<title>Jjfdez at 09:05, 8 September 2009</title>
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		<updated>2009-09-08T09:05:50Z</updated>

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&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;== Citation ==&lt;br /&gt;
Fernandez JJ, Li S, Lucic V. Three-dimensional anisotropic noise reduction with automated parameter tuning. Application to electron cryotomography. Lecture Notes in Computer Science, 4788:60-69, 2007. &lt;br /&gt;
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== Abstract ==&lt;br /&gt;
This article presents an approach for noise filtering that is based on anisotropic nonlinear diffusion. The method combines edge-preserving noise reduction with a strategy to enhance local structures and a mechanism to further smooth the background. We have provided the method with an automatic mechanism for parameter self-tuning and for stopping the iterative filtering process. The performance of the approach is illustrated with its application to electron cryotomography (cryoET). CryoET has emerged as a leading imaging technique for visualizing the molecular architecture of complex biological specimens. A challenging computational task in this discipline is to increase the extremely low signal-to-noise ratio (SNR) to allow visualization and interpretation of the three-dimensional structures. The filtering method here proposed succeeds in substantially reducing the noise with excellent preservation of the structures.&lt;br /&gt;
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== Keywords ==&lt;br /&gt;
Electron tomography; Denoising; Anisotropic nonlinear diffusion&lt;br /&gt;
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== Links ==&lt;br /&gt;
Article: http://dx.doi.org/10.1007/978-3-540-75271-4_7&lt;br /&gt;
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== Related software ==&lt;br /&gt;
[http://www.ual.es/~jjfdez/SW/tomoand.html TOMOAND]&lt;br /&gt;
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== Related methods ==&lt;br /&gt;
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== Comments ==&lt;/div&gt;</summary>
		<author><name>Jjfdez</name></author>
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