https://3demmethods.i2pc.es/index.php?action=history&feed=atom&title=2014Bai_Review 2026-05-24T22:01:30Z Revision history for this page on the wiki MediaWiki 1.44.2 https://3demmethods.i2pc.es/index.php?title=2014Bai_Review&diff=2599&oldid=prev 2014-12-29T09:08:40Z

<p>Created page with &quot;== Citation == Bai, X.-C.; McMullan, G. &amp; Scheres, S. H. How cryo-EM is revolutionizing structural biology Trends in Biochemical Sciences, Elsevier, 2014, 40, 49-57 == Abstr...&quot;</p> <p><b>New page</b></p><div>== Citation ==<br /> <br /> Bai, X.-C.; McMullan, G. &amp; Scheres, S. H. How cryo-EM is revolutionizing structural biology Trends in Biochemical Sciences, Elsevier, 2014, 40, 49-57<br /> <br /> == Abstract ==<br /> <br /> For many years, structure determination of biological macromolecules by cryo-electron microscopy (cryo-EM) was limited to large complexes or low-resolution models. With recent advances in electron detection and image processing, the resolution by cryo-EM is now beginning to rival X-ray crystallography. A new generation of electron detectors record images with unprecedented quality, while new image-processing tools correct for sample movements and classify images according to different structural states. Combined, these advances yield density maps with sufficient detail to deduce the atomic structure for a range of specimens. Here, we review the recent advances and illustrate the exciting new opportunities that they offer to structural biology research.<br /> <br /> == Keywords ==<br /> <br /> == Links ==<br /> <br /> http://www.sciencedirect.com/science/article/pii/S096800041400187X<br /> <br /> == Related software ==<br /> <br /> == Related methods ==<br /> <br /> == Comments ==</div>

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