https://3demmethods.i2pc.es/index.php?action=history&feed=atom&title=2014Politis_MassSpect 2026-06-13T12:12:48Z Revision history for this page on the wiki MediaWiki 1.44.2 https://3demmethods.i2pc.es/index.php?title=2014Politis_MassSpect&diff=2665&oldid=prev 2015-06-10T15:14:03Z

<p>Created page with &quot;== Citation == Politis, A.; Stengel, F.; Hall, Z.; Hernández, H.; Leitner, A.; Walzthoeni, T.; Robinson, C. V. &amp; Aebersold, R. A mass spectrometry-based hybrid method for st...&quot;</p> <p><b>New page</b></p><div>== Citation ==<br /> <br /> Politis, A.; Stengel, F.; Hall, Z.; Hernández, H.; Leitner, A.; Walzthoeni, T.; Robinson, C. V. &amp; Aebersold, R. A mass spectrometry-based hybrid method for structural modeling of protein complexes. Nat Methods, 2014, 11, 403-406<br /> <br /> == Abstract ==<br /> <br /> We describe a method that integrates data derived from different mass spectrometry (MS)-based techniques with a modeling strategy for structural characterization of protein assemblies. We encoded structural data derived from native MS, bottom-up proteomics, ion mobility-MS and chemical cross-linking MS into modeling restraints to compute the most likely structure of a protein assembly. We used the method to generate near-native models for three known structures and characterized an assembly intermediate of the proteasomal base.<br /> <br /> == Keywords ==<br /> <br /> == Links ==<br /> <br /> http://www.nature.com/nmeth/journal/v11/n4/full/nmeth.2841.html<br /> <br /> == Related software ==<br /> <br /> == Related methods ==<br /> <br /> == Comments ==</div>

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