https://3demmethods.i2pc.es/index.php?action=history&feed=atom&title=2016Beck_Review 2026-05-24T20:15:34Z Revision history for this page on the wiki MediaWiki 1.44.2 https://3demmethods.i2pc.es/index.php?title=2016Beck_Review&diff=3048&oldid=prev 2017-02-21T15:31:10Z

<p>Created page with &quot;== Citation == Beck, M. &amp; Baumeister, W. Cryo-Electron Tomography: Can it Reveal the Molecular Sociology of Cells in Atomic Detail? Trends in cell biology, 2016, 26, 825-837...&quot;</p> <p><b>New page</b></p><div>== Citation ==<br /> <br /> Beck, M. &amp; Baumeister, W. Cryo-Electron Tomography: Can it Reveal the Molecular Sociology of Cells in Atomic Detail? Trends in cell biology, 2016, 26, 825-837<br /> <br /> == Abstract ==<br /> <br /> Traditionally, macromolecular structure determination is performed ex situ, that is, with purified materials. But, there are strong incentives to develop approaches to study them in situ in their native functional context. In recent years, cryo-electron tomography (cryo-ET) has emerged as a powerful method for visualizing the molecular organization of unperturbed cellular landscapes with the potential to attain near-atomic resolution. Here, we review recent work on several macromolecular assemblies, demonstrating the power of in situ studies. We also highlight technical challenges and discuss ways to meet them.<br /> <br /> == Keywords ==<br /> <br /> == Links ==<br /> <br /> http://www.cell.com/trends/cell-biology/fulltext/S0962-8924(16)30123-4<br /> <br /> == Related software ==<br /> <br /> == Related methods ==<br /> <br /> == Comments ==</div>

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