https://3demmethods.i2pc.es/index.php?action=history&feed=atom&title=2016Koeck_ADF 2026-05-24T22:00:57Z Revision history for this page on the wiki MediaWiki 1.44.2 https://3demmethods.i2pc.es/index.php?title=2016Koeck_ADF&diff=2782&oldid=prev 2015-12-28T11:30:17Z

<p>Created page with &quot;== Citation == Koeck, P. J. B. Annular dark field transmission electron microscopy for protein structure determination. Ultramicroscopy, 2016, 161, 98-104 == Abstract == Re...&quot;</p> <p><b>New page</b></p><div>== Citation ==<br /> <br /> Koeck, P. J. B. Annular dark field transmission electron microscopy for protein structure determination. Ultramicroscopy, 2016, 161, 98-104<br /> <br /> == Abstract ==<br /> <br /> Recently annular dark field (ADF) transmission electron microscopy (TEM) has been advocated as a means of recording images of biological specimens with better signal to noise ratio (SNR) than regular bright field images. I investigate whether and how such images could be used to determine the three-dimensional structure of proteins given that an ADF aperture with a suitable pass-band can be manufactured and used in practice. I develop an approximate theory of ADF-TEM image formation for weak amplitude and phase objects and test this theory using computer simulations. I also test whether these simulated images can be used to calculate a three-dimensional model of the protein using standard software and discuss problems and possible ways to overcome these.<br /> <br /> == Keywords ==<br /> <br /> == Links ==<br /> <br /> http://www.ncbi.nlm.nih.gov/pubmed/26656466<br /> <br /> == Related software ==<br /> <br /> == Related methods ==<br /> <br /> == Comments ==</div>

CoSS