Coss: Created page with "== Citation == Chen, M.; Dai, W.; Sun, S. Y.; Jonasch, D.; He, C. Y.; Schmid, M. F.; Chiu, W. & Ludtke, S. J. Convolutional neural networks for automated annotation of cellul..."

2017-10-07T18:57:37Z

Created page with "== Citation == Chen, M.; Dai, W.; Sun, S. Y.; Jonasch, D.; He, C. Y.; Schmid, M. F.; Chiu, W. & Ludtke, S. J. Convolutional neural networks for automated annotation of cellul..."

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== Citation ==

Chen, M.; Dai, W.; Sun, S. Y.; Jonasch, D.; He, C. Y.; Schmid, M. F.; Chiu, W. & Ludtke, S. J. Convolutional neural networks for automated annotation of cellular cryo-electron tomograms. Nature methods, 2017, 14, 983-985

== Abstract ==

Cellular electron cryotomography offers researchers the ability to observe macromolecules frozen in action in situ, but a primary challenge with this technique is identifying molecular components within the crowded cellular environment. We introduce a method that uses neural networks to dramatically reduce the time and human effort required for subcellular annotation and feature extraction. Subsequent subtomogram classification and averaging yield in situ structures of molecular components of interest. The method is available in the EMAN2.2 software package.

== Keywords ==

== Links ==

http://www.nature.com/nmeth/journal/v14/n10/full/nmeth.4405.html

== Related software ==

== Related methods ==

== Comments ==

2017Chen Annotation - Revision history

Coss: Created page with "== Citation == Chen, M.; Dai, W.; Sun, S. Y.; Jonasch, D.; He, C. Y.; Schmid, M. F.; Chiu, W. & Ludtke, S. J. Convolutional neural networks for automated annotation of cellul..."