https://3demmethods.i2pc.es/index.php?action=history&feed=atom&title=2017Jonic_Review 2026-05-24T22:01:21Z Revision history for this page on the wiki MediaWiki 1.44.2 https://3demmethods.i2pc.es/index.php?title=2017Jonic_Review&diff=3036&oldid=prev 2017-01-13T19:56:55Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 19:56, 13 January 2017</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Citation ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Citation ==</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>S. <del style="font-weight: bold; text-decoration: none;">Jonic (2017) </del>Computational methods for analyzing conformational variability of macromolecular complexes from cryo-electron microscopy images. Current Opinion in Structural Biology 43<del style="font-weight: bold; text-decoration: none;">:</del>114–121<del style="font-weight: bold; text-decoration: none;">.</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Jonic, </ins>S. Computational methods for analyzing conformational variability of macromolecular complexes from cryo-electron microscopy images. Current Opinion in Structural Biology<ins style="font-weight: bold; text-decoration: none;">, 2017, </ins>43<ins style="font-weight: bold; text-decoration: none;">, </ins>114–121</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Abstract ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Abstract ==</div></td></tr> </table>

Sjonic https://3demmethods.i2pc.es/index.php?title=2017Jonic_Review&diff=3035&oldid=prev 2017-01-13T19:51:52Z

<p>Created page with &quot;== Citation == S. Jonic (2017) Computational methods for analyzing conformational variability of macromolecular complexes from cryo-electron microscopy images. Current Opinion...&quot;</p> <p><b>New page</b></p><div>== Citation ==<br /> S. Jonic (2017) Computational methods for analyzing conformational variability of macromolecular complexes from cryo-electron microscopy images. Current Opinion in Structural Biology 43:114–121.<br /> <br /> == Abstract ==<br /> Thanks to latest technical advances in cryo-electron microscopy (cryo-EM), structures of macromolecular complexes (viruses, ribosomes, etc.) are now often obtained at near-atomic resolution. Also, studies of conformational changes of complexes, in connection with their function, are gaining ground. Conformational variability analysis is usually done by classifying images in a number of discrete classes supposedly representing all conformational states present in the specimen. However, discrete classes cannot be meaningfully defined when the conformational change is continuous (the specimen contains a continuum of states instead of a few discrete states). For such cases, first image analysis methods that explicitly consider continuous conformational changes were recently developed. The latest developments in cryo-EM image analysis methods for conformational variability analysis are the focus of this review.<br /> <br /> == Keywords ==<br /> Structure; dynamics; macromolecular complexes; cryo-electron microscopy; conformational changes; single-particle analysis<br /> <br /> <br /> == Links ==<br /> http://dx.doi.org/10.1016/j.sbi.2016.12.011<br /> <br /> <br /> == Related software ==<br /> <br /> == Related methods ==<br /> <br /> == Comments ==</div>

Sjonic