WikiSysop: Created page with "== Citation == Cassidy, C. K.; Himes, B. A.; Luthey-Schulten, Z. & Zhang, P. CryoEM-based hybrid modeling approaches for structure determination. Current opinion in micro..."

2018-12-26T20:19:18Z

Created page with "== Citation == Cassidy, C. K.; Himes, B. A.; Luthey-Schulten, Z. & Zhang, P. CryoEM-based hybrid modeling approaches for structure determination. Current opinion in micro..."

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== Citation ==

Cassidy, C. K.; Himes, B. A.; Luthey-Schulten, Z. & Zhang, P. CryoEM-based hybrid modeling approaches for structure determination. Current opinion in microbiology, 2018, 43, 14-23

== Abstract ==

ecent advances in cryo-electron microscopy (cryoEM) have dramatically improved the resolutions at which vitrified biological specimens can be studied, revealing new structural and mechanistic insights over a broad range of spatial scales. Bolstered by these advances, much effort has been directed toward the development of hybrid modeling methodologies for the construction and refinement of high-fidelity atomistic models from cryoEM data. In this brief review, we will survey the key elements of cryoEM-based hybrid modeling, providing an overview of available computational tools and strategies as well as several recent applications.

== Keywords ==

== Links ==

https://www.ncbi.nlm.nih.gov/pubmed/29107896

== Related software ==

== Related methods ==

== Comments ==

2018Cassidy review - Revision history

WikiSysop: Created page with "== Citation == Cassidy, C. K.; Himes, B. A.; Luthey-Schulten, Z. & Zhang, P. CryoEM-based hybrid modeling approaches for structure determination. Current opinion in micro..."