https://3demmethods.i2pc.es/index.php?action=history&feed=atom&title=2019Benjin_Review 2026-05-24T20:20:57Z Revision history for this page on the wiki MediaWiki 1.44.2 https://3demmethods.i2pc.es/index.php?title=2019Benjin_Review&diff=3597&oldid=prev 2019-12-27T07:45:36Z

<p>Created page with &quot;== Citation == Benjin, X. &amp; Ling, L. Developments, applications, and prospects of cryo-electron microscopy. Protein science, 2019, 1-11 == Abstract == Cryo-electron micros...&quot;</p> <p><b>New page</b></p><div>== Citation ==<br /> <br /> Benjin, X. &amp; Ling, L.<br /> Developments, applications, and prospects of cryo-electron microscopy. <br /> Protein science, 2019, 1-11<br /> <br /> == Abstract ==<br /> <br /> Cryo-electron microscopy (cryo-EM) is a structural biological method that is used to determine the 3D structures of biomacromolecules. After years of development, cryo-EM has made great achievements, which has led to a revolution in structural biology. In this article, the principle, characteristics, history, current situation, workflow, and common problems of cryo-EM are systematically reviewed. In addition, the new development direction of cryo-EM-cryo-electron tomography (cryo-ET), is discussed in detail. Also, cryo-EM is prospected from the following aspects: the structural analysis of small proteins, the improvement of resolution and efficiency, and the relationship between cryo-EM and drug development. This review is dedicated to giving readers a comprehensive understanding of the development and application of cryo-EM, and to bringing them new insights.<br /> <br /> == Keywords ==<br /> <br /> == Links ==<br /> <br /> https://onlinelibrary.wiley.com/doi/pdf/10.1002/pro.3805<br /> <br /> == Related software ==<br /> <br /> == Related methods ==<br /> <br /> == Comments ==</div>

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