https://3demmethods.i2pc.es/index.php?action=history&feed=atom&title=2020Lai_Statistics 2026-05-24T19:43:41Z Revision history for this page on the wiki MediaWiki 1.44.2 https://3demmethods.i2pc.es/index.php?title=2020Lai_Statistics&diff=3873&oldid=prev 2021-02-03T08:25:03Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 08:25, 3 February 2021</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Citation ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Citation ==</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Lai, T. L.; Wang, S.-H.; Yao, Y.-C.; Chung, S.-C.; Chang, W.-H.; Tu, I.-P. Cryo-EM: breakthroughs in chemistry, structural biology, and statistical underpinnings, Stanford Univ.,  </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Lai, T. L.; Wang, S.-H.; Yao, Y.-C.; Chung, S.-C.; Chang, W.-H.; Tu, I.-P. Cryo-EM: breakthroughs in chemistry, structural biology, and statistical underpinnings, Stanford Univ., TechReport Dept. Statistics 2020-14, 2020</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"> </del>TechReport Dept. Statistics 2020-14, 2020</div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Abstract ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Abstract ==</div></td></tr> </table>

WikiSysop https://3demmethods.i2pc.es/index.php?title=2020Lai_Statistics&diff=3872&oldid=prev 2021-02-03T08:24:51Z

<p>Created page with &quot;== Citation == Lai, T. L.; Wang, S.-H.; Yao, Y.-C.; Chung, S.-C.; Chang, W.-H.; Tu, I.-P. Cryo-EM: breakthroughs in chemistry, structural biology, and statistical underpinnin...&quot;</p> <p><b>New page</b></p><div>== Citation ==<br /> <br /> Lai, T. L.; Wang, S.-H.; Yao, Y.-C.; Chung, S.-C.; Chang, W.-H.; Tu, I.-P. Cryo-EM: breakthroughs in chemistry, structural biology, and statistical underpinnings, Stanford Univ., <br /> TechReport Dept. Statistics 2020-14, 2020<br /> <br /> == Abstract ==<br /> <br /> Cryogenic electron microscopy (cryo-EM) has revolutionized structural biology, organic and medicinal chemistry, molecular and cellular physiology, and its fundamental<br /> importance was recognized in the 2017 Nobel Prize in Chemistry. Herein we �first review<br /> the statistical underpinnings of high-resolution 3D image reconstruction from 2D cryo-EM<br /> data that have three characteristic features: missing data, high noise level, and massive<br /> datasets. We then discuss challenges and opportunities for statistical science posed by<br /> high-resolution structure determination using cryo-EM, and review recent advances in<br /> high-dimensional multivariate analysis, dimension reduction, maximum a posteriori estimation of latent variables, hidden Markov models and uncertainty quanti�cation in this<br /> connection.<br /> <br /> == Keywords ==<br /> <br /> == Links ==<br /> <br /> https://statistics.stanford.edu/sites/g/files/sbiybj6031/f/2020-14.pdf<br /> <br /> == Related software ==<br /> <br /> == Related methods ==<br /> <br /> == Comments ==</div>

WikiSysop