https://3demmethods.i2pc.es/index.php?action=history&feed=atom&title=2020McCafferty_Review 2026-05-24T19:35:26Z Revision history for this page on the wiki MediaWiki 1.44.2 https://3demmethods.i2pc.es/index.php?title=2020McCafferty_Review&diff=3768&oldid=prev 2020-07-28T01:25:37Z

<p>Created page with &quot;== Citation == McCafferty, C. L.; Verbeke, E. J.; Marcotte, E. M.; Taylor, D. W. Structural Biology in the Multi-Omics Era. Journal of chemical information and modeling, 2020...&quot;</p> <p><b>New page</b></p><div>== Citation ==<br /> <br /> McCafferty, C. L.; Verbeke, E. J.; Marcotte, E. M.; Taylor, D. W. Structural Biology in the Multi-Omics Era. Journal of chemical information and modeling, 2020, 60, 2424-2429 <br /> <br /> == Abstract ==<br /> <br /> Rapid developments in cryogenic electron microscopy have opened new avenues to probe the structures of protein assemblies in their near native states. Recent studies have begun applying single -particle analysis to heterogeneous mixtures, revealing the potential of structural-omics approaches that combine the power of mass spectrometry and electron microscopy. Here we highlight advances and challenges in sample preparation, data processing, and molecular modeling for handling increasingly complex mixtures. Such advances will help structural-omics methods extend to cellular-level models of structural biology. <br /> <br /> == Keywords ==<br /> <br /> == Links ==<br /> <br /> https://pubs.acs.org/doi/10.1021/acs.jcim.9b01164<br /> <br /> == Related software ==<br /> <br /> == Related methods ==<br /> <br /> == Comments ==</div>

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