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	<title>2020Miolane VAEGAN - Revision history</title>
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	<updated>2026-06-13T13:46:24Z</updated>
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		<title>WikiSysop: Created page with &quot;== Citation ==  Miolane, N.; Poitevin, F.; Li, Y.-T., Holmes, S. Estimation of orientation and camera parameters from cryo-electron microscopy images with variational autoenco...&quot;</title>
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		<updated>2020-07-09T07:23:38Z</updated>

		<summary type="html">&lt;p&gt;Created page with &amp;quot;== Citation ==  Miolane, N.; Poitevin, F.; Li, Y.-T., Holmes, S. Estimation of orientation and camera parameters from cryo-electron microscopy images with variational autoenco...&amp;quot;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;== Citation ==&lt;br /&gt;
&lt;br /&gt;
Miolane, N.; Poitevin, F.; Li, Y.-T., Holmes, S. Estimation of orientation and camera parameters from cryo-electron microscopy images with variational autoencoders and generative adversarial networks, Proc. IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops, 2020, 970-971 &lt;br /&gt;
&lt;br /&gt;
== Abstract ==&lt;br /&gt;
&lt;br /&gt;
Cryo-electron microscopy (cryo-EM) is capable of producing reconstructed 3D images of biomolecules at nearatomic resolution. However, raw cryo-EM images are only&lt;br /&gt;
highly corrupted - noisy and band-pass filtered - 2D projections of the target 3D biomolecules. Reconstructing the 3D&lt;br /&gt;
molecular shape requires the estimation of the orientation&lt;br /&gt;
of the biomolecule that has produced the given 2D image,&lt;br /&gt;
and the estimation of camera parameters to correct for intensity defects. Current techniques performing these tasks&lt;br /&gt;
are often computationally expensive, while the dataset sizes&lt;br /&gt;
keep growing. There is a need for next-generation algorithms that preserve accuracy while improving speed and&lt;br /&gt;
scalability. In this paper, we combine variational autoencoders (VAEs) and generative adversarial networks (GANs)&lt;br /&gt;
to learn a low-dimensional latent representation of cryoEM images. This analysis leads us to design an estimation&lt;br /&gt;
method for orientation and camera parameters of singleparticle cryo-EM images, which opens the door to faster&lt;br /&gt;
cryo-EM biomolecule reconstruction.&lt;br /&gt;
&lt;br /&gt;
== Keywords ==&lt;br /&gt;
&lt;br /&gt;
== Links ==&lt;br /&gt;
&lt;br /&gt;
https://openaccess.thecvf.com/content_CVPRW_2020/papers/w57/Miolane_Estimation_of_Orientation_and_Camera_Parameters_From_Cryo-Electron_Microscopy_Images_CVPRW_2020_paper.pdf&lt;br /&gt;
&lt;br /&gt;
== Related software ==&lt;br /&gt;
&lt;br /&gt;
== Related methods ==&lt;br /&gt;
&lt;br /&gt;
== Comments ==&lt;/div&gt;</summary>
		<author><name>WikiSysop</name></author>
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