WikiSysop: Created page with "== Citation == Sorzano, C. O. S. / Vilas, J. L. / Ram\irez-Aportela, Erney / Krieger, J. / Del Hoyo, D. / de Isidro-Gómez, F. / Herreros, David / Fernandez-Giménez, Estrell..."

2023-06-28T07:17:13Z

Created page with "== Citation == Sorzano, C. O. S. / Vilas, J. L. / Ram\irez-Aportela, Erney / Krieger, J. / Del Hoyo, D. / de Isidro-Gómez, F. / Herreros, David / Fernandez-Giménez, Estrell..."

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== Citation ==

Sorzano, C. O. S. / Vilas, J. L. / Ram\irez-Aportela, Erney / Krieger, J. / Del Hoyo, D. / de Isidro-Gómez, F. / Herreros, David / Fernandez-Giménez, Estrella / Marchán, D. / Mac\ias, J. R. / Sánchez, I. / del Caño, L. / Fonseca-Reyna, Y. / Conesa, P. / García-Mena, A. / Burguet, J. / García-Condado, J. / Méndez-García, J. / Martínez, M. / Muñoz-Barrutia, A. / Marabini, R. / Vargas, J. / Carazo, J. M. Image processing tools for the validation of CryoEM maps. 2022. Faraday Discussions, Vol. 240, p. 210-227

== Abstract ==

The number of maps deposited in public databases (Electron Microscopy Data Bank,
EMDB) determined by cryo-electron microscopy has quickly grown in recent years.
With this rapid growth, it is critical to guarantee their quality. So far, map validation has
primarily focused on the agreement between maps and models. From the image
processing perspective, the validation has been mostly restricted to using two halfmaps
and the measurement of their internal consistency. In this article, we suggest that
map validation can be taken much further from the point of view of image processing if
2D classes, particles, angles, coordinates, defoci, and micrographs are also provided. We
present a progressive validation scheme that qualifies a result validation status from 0 to
5 and offers three optional qualifiers (A, W, and O) that can be added. The simplest
validation state is 0, while the most complete would be 5AWO. This scheme has been
implemented in a website https://biocomp.cnb.csic.es/EMValidationService/ to which
reconstructed maps and their ESI can be uploaded.

== Keywords ==

== Links ==

https://pubs.rsc.org/en/content/articlehtml/2022/fd/d2fd00059h

== Related software ==

== Related methods ==

== Comments ==

2022Sorzano Validation - Revision history

WikiSysop: Created page with "== Citation == Sorzano, C. O. S. / Vilas, J. L. / Ram\irez-Aportela, Erney / Krieger, J. / Del Hoyo, D. / de Isidro-Gómez, F. / Herreros, David / Fernandez-Giménez, Estrell..."