https://3demmethods.i2pc.es/index.php?action=history&feed=atom&title=2022Vargas_tubular 2026-05-24T20:25:10Z Revision history for this page on the wiki MediaWiki 1.44.2 https://3demmethods.i2pc.es/index.php?title=2022Vargas_tubular&diff=4185&oldid=prev 2022-03-23T21:02:32Z

<p>Created page with &quot;== Citation == Vargas, Javier / Gómez-Pedrero, José A. / Quiroga, J. Antonio / Alonso, José. Enhancement of Cryo-EM maps by a multiscale tubular filter. 2022-01, Optics ex...&quot;</p> <p><b>New page</b></p><div>== Citation ==<br /> <br /> Vargas, Javier / Gómez-Pedrero, José A. / Quiroga, J. Antonio / Alonso, José. Enhancement of Cryo-EM maps by a multiscale tubular filter. 2022-01, Optics express, Vol. 30, p. 4515-4527<br /> <br /> == Abstract ==<br /> <br /> Abstract: &lt;/b&gt;We present an approach to enhance cryo-electron microscopy (cryo-EM) postprocessed maps based on a multiscale tubular filter. The method determines a tubularness measure locally by the analysis of the eigenvalues of the Hessian matrix. This information is used to enhance elongated local structures and to attenuate blob-like and plate-like structures. The approach, thus, introduces a priori information in the reconstructions to improve their interpretability and analysis at high-resolution. The proposed method has been tested with simulated and real cryo-EM maps including recent reconstructions of the SARS-CoV-2. Our results show that our methods can improve obtained reconstructions. <br /> <br /> == Keywords ==<br /> <br /> == Links ==<br /> <br /> https://opg.optica.org/oe/fulltext.cfm?uri=oe-30-3-4515&amp;id=468839<br /> <br /> == Related software ==<br /> <br /> == Related methods ==<br /> <br /> == Comments ==</div>

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