https://3demmethods.i2pc.es/index.php?action=history&feed=atom&title=2022Wang_Review 2026-05-24T19:36:17Z Revision history for this page on the wiki MediaWiki 1.44.2 https://3demmethods.i2pc.es/index.php?title=2022Wang_Review&diff=4194&oldid=prev 2022-03-23T21:26:05Z

<p>Created page with &quot;== Citation == Wang, Fengbin / Gnewou, Ordy / Solemanifar, Armin / Conticello, Vincent P. / Egelman, Edward H. Cryo-EM of Helical Polymers. 2022-02, Chemical reviews == Abst...&quot;</p> <p><b>New page</b></p><div>== Citation ==<br /> <br /> Wang, Fengbin / Gnewou, Ordy / Solemanifar, Armin / Conticello, Vincent P. / Egelman, Edward H. Cryo-EM of Helical Polymers. 2022-02, Chemical reviews<br /> <br /> == Abstract ==<br /> <br /> While the application of cryogenic electron microscopy (cryo-EM) to helical polymers in biology has a long history, due to the huge number of helical macromolecular assemblies in viruses, bacteria, archaea, and eukaryotes, the use of cryo-EM to study synthetic soft matter noncovalent polymers has been much more limited. This has mainly been due to the lack of familiarity with cryo-EM in the materials science and chemistry communities, in contrast to the fact that cryo-EM was developed as a biological technique. Nevertheless, the relatively few structures of self-assembled peptide nanotubes and ribbons solved at near-atomic resolution by cryo-EM have demonstrated that cryo-EM should be the method of choice for a structural analysis of synthetic helical filaments. In addition, cryo-EM has also demonstrated that the self-assembly of soft matter polymers has enormous potential for polymorphism, something that may be obscured by techniques such as scattering and spectroscopy. These cryo-EM structures have revealed how far we currently are from being able to predict the structure of these polymers due to their chaotic self-assembly behavior. <br /> <br /> == Keywords ==<br /> <br /> == Links ==<br /> <br /> https://pubs.acs.org/doi/10.1021/acs.chemrev.1c00753<br /> <br /> == Related software ==<br /> <br /> == Related methods ==<br /> <br /> == Comments ==</div>

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