https://3demmethods.i2pc.es/index.php?action=history&feed=atom&title=2023Ochner_Review 2026-05-24T20:20:49Z Revision history for this page on the wiki MediaWiki 1.44.2 https://3demmethods.i2pc.es/index.php?title=2023Ochner_Review&diff=4535&oldid=prev 2024-01-12T08:25:05Z

<p>Created page with &quot;== Citation == Ochner, Hannah / Bharat, Tanmay A. M. Charting the molecular landscape of the cell. 2023. Structure, Vol. 31, No. 11, p. 1297-1305 == Abstract == Biological...&quot;</p> <p><b>New page</b></p><div>== Citation ==<br /> <br /> Ochner, Hannah / Bharat, Tanmay A. M. Charting the molecular landscape of the cell. 2023. Structure, Vol. 31, No. 11, p. 1297-1305 <br /> <br /> == Abstract ==<br /> <br /> Biological function of macromolecules is closely tied to their cellular location, as well as to interactions with<br /> other molecules within the native environment of the cell. Therefore, to obtain detailed mechanistic insights<br /> into macromolecular functionality, one of the outstanding targets for structural biology is to produce an<br /> atomic-level understanding of the cell. One structural biology technique that has already been used to<br /> directly derive atomic models of macromolecules from cells, without any additional external information, is<br /> electron cryotomography (cryoET). In this perspective article, we discuss possible routes to chart the molecular<br /> landscape of the cell by advancing cryoET imaging as well as by embedding cryoET into correlative imaging<br /> workflows.<br /> <br /> == Keywords ==<br /> <br /> == Links ==<br /> <br /> https://www.cell.com/structure/pdf/S0969-2126(23)00290-3.pdf<br /> <br /> == Related software ==<br /> <br /> == Related methods ==<br /> <br /> == Comments ==</div>

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