WikiSysop: Created page with "== Citation == Střelák, David / Marchán, Daniel / Carazo, José Mar\ia / S. Sorzano, Carlos O. Performance and Quality Comparison of Movie Alignment Software for Cryogenic..."

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Created page with "== Citation == Střelák, David / Marchán, Daniel / Carazo, José Mar\ia / S. Sorzano, Carlos O. Performance and Quality Comparison of Movie Alignment Software for Cryogenic..."

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== Citation ==

Střelák, David / Marchán, Daniel / Carazo, José Mar\ia / S. Sorzano, Carlos O. Performance and Quality Comparison of Movie Alignment Software for Cryogenic Electron Microscopy. 2023. Micromachines, Vol. 14, No. 10, p. 1835

== Abstract ==

Cryogenic electron microscopy (Cryo-EM) has been established as one of the key players in
structural biology. It can reconstruct a 3D model of a sample at a near-atomic resolution. With the
increasing number of facilities, faster microscopes, and new imaging techniques, there is a growing
demand for algorithms and programs able to process the so-called movie data produced by the
microscopes in real time while preserving a high resolution and maximal information. In this article,
we conduct a comparative analysis of the quality and performance of the most commonly used
software for movie alignment. More precisely, we compare the most recent versions of FlexAlign
(Xmipp v3.23.03), MotionCor2 (v1.6.4), Relion MotionCor (v4.0-beta), Warp (v1.0.9), and CryoSPARC
(v4.0.3). We tested the quality of the alignment using generated phantom data, as well as real datasets,
comparing the alignment precision, power spectra density, and performance scaling of each program.

== Keywords ==

== Links ==

https://www.mdpi.com/2072-666X/14/10/1835

== Related software ==

== Related methods ==

== Comments ==

2023Strelak MovieAlignment - Revision history

WikiSysop: Created page with "== Citation == Střelák, David / Marchán, Daniel / Carazo, José Mar\ia / S. Sorzano, Carlos O. Performance and Quality Comparison of Movie Alignment Software for Cryogenic..."