https://3demmethods.i2pc.es/index.php?action=history&feed=atom&title=2024Bock_MD2024Bock MD - Revision history2026-05-24T21:07:01ZRevision history for this page on the wikiMediaWiki 1.44.2https://3demmethods.i2pc.es/index.php?title=2024Bock_MD&diff=4693&oldid=prevWikiSysop: Created page with "== Citation == Bock, Lars V. / Igaev, Maxim / Grubmüller, Helmut. Single-particle Cryo-EM and molecular dynamics simulations: A perfect match. 2024. Current Opinion in Structural Biology, Vol. 86, p. 102825 == Abstract == Knowledge of the structure and dynamics of biomolecules is key to understanding the mechanisms underlying their biological functions. Single-particle cryo-electron microscopy (cryo-EM) is a powerful structural biology technique to characterize compl..."2024-08-14T06:31:04Z<p>Created page with "== Citation == Bock, Lars V. / Igaev, Maxim / Grubmüller, Helmut. Single-particle Cryo-EM and molecular dynamics simulations: A perfect match. 2024. Current Opinion in Structural Biology, Vol. 86, p. 102825 == Abstract == Knowledge of the structure and dynamics of biomolecules is key to understanding the mechanisms underlying their biological functions. Single-particle cryo-electron microscopy (cryo-EM) is a powerful structural biology technique to characterize compl..."</p>
<p><b>New page</b></p><div>== Citation ==<br />
<br />
Bock, Lars V. / Igaev, Maxim / Grubmüller, Helmut. Single-particle Cryo-EM and molecular dynamics simulations: A perfect match. 2024. Current Opinion in Structural Biology, Vol. 86, p. 102825<br />
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== Abstract ==<br />
<br />
Knowledge of the structure and dynamics of biomolecules is<br />
key to understanding the mechanisms underlying their biological<br />
functions. Single-particle cryo-electron microscopy<br />
(cryo-EM) is a powerful structural biology technique to<br />
characterize complex biomolecular systems. Here, we<br />
review recent advances of how Molecular Dynamics (MD)<br />
simulations are being used to increase and enhance the<br />
information extracted from cryo-EM experiments. We will<br />
particularly focus on the physics underlying these experiments,<br />
how MD facilitates structure refinement, in particular<br />
for heterogeneous and non-isotropic resolution, and how<br />
thermodynamic and kinetic information can be extracted<br />
from cryo-EM data.<br />
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== Keywords ==<br />
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== Links ==<br />
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https://www.sciencedirect.com/science/article/pii/S0959440X24000526<br />
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== Related software ==<br />
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== Related methods ==<br />
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== Comments ==</div>WikiSysop