https://3demmethods.i2pc.es/index.php?action=history&feed=atom&title=2025Starynska_Membrane2025Starynska Membrane - Revision history2026-07-07T19:06:27ZRevision history for this page on the wikiMediaWiki 1.44.2https://3demmethods.i2pc.es/index.php?title=2025Starynska_Membrane&diff=5224&oldid=prevWikiSysop: Created page with "== Citation == Starynska, A., Cameron, C.J., Sigworth, F.J. and Tagare, H.D. 2026. Automated Membrane Detection and Subtraction for Structure Determination of Membrane Proteins in Cryogenic Electron Microscopy. Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition (2026), 6553–6562. == Abstract == High-resolution cryo-electron microscopy (cryo-EM) reconstruction of membrane proteins often requires the bilayer membrane containing the prote..."2026-07-07T06:17:51Z<p>Created page with "== Citation == Starynska, A., Cameron, C.J., Sigworth, F.J. and Tagare, H.D. 2026. Automated Membrane Detection and Subtraction for Structure Determination of Membrane Proteins in Cryogenic Electron Microscopy. Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition (2026), 6553–6562. == Abstract == High-resolution cryo-electron microscopy (cryo-EM) reconstruction of membrane proteins often requires the bilayer membrane containing the prote..."</p>
<p><b>New page</b></p><div>== Citation ==<br />
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Starynska, A., Cameron, C.J., Sigworth, F.J. and Tagare, H.D. 2026. Automated Membrane Detection and Subtraction for Structure Determination of Membrane Proteins in Cryogenic Electron Microscopy. Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition (2026), 6553–6562.<br />
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== Abstract ==<br />
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High-resolution cryo-electron microscopy (cryo-EM) reconstruction<br />
of membrane proteins often requires the bilayer<br />
membrane containing the protein to be subtracted<br />
from the image. We propose a two-step machine learning<br />
framework for this task: (1) membrane detection, which<br />
identifies the bilayer membrane, and (2) membrane subtraction,<br />
which digitally removes the detected membrane<br />
from the cryo-EM image. Recent work has introduced algorithms<br />
for membrane detection, but membrane subtraction<br />
remains relatively underexplored. Here, we present<br />
a novel unsupervised approach for membrane subtraction<br />
which computes a smooth estimate of the membrane that<br />
can be subtracted from the original cryo-EM image. Experimental<br />
results show that our method outperforms existing<br />
membrane subtraction alternatives and enables reliable 3D<br />
reconstruction of membrane proteins.<br />
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== Keywords ==<br />
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== Links ==<br />
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https://openaccess.thecvf.com/content/CVPR2026W/CVMI/html/Starynska_Automated_Membrane_Detection_and_Subtraction_for_Structure_Determination_of_Membrane_CVPRW_2026_paper.html<br />
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== Related software ==<br />
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== Related methods ==<br />
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== Comments ==</div>WikiSysop