https://3demmethods.i2pc.es/index.php?action=history&feed=atom&title=2025Wan_Review2025Wan Review - Revision history2026-05-24T19:36:10ZRevision history for this page on the wikiMediaWiki 1.44.2https://3demmethods.i2pc.es/index.php?title=2025Wan_Review&diff=5030&oldid=prevWikiSysop: Created page with "== Citation == W. Wan, “A practical look at cryo-electron tomography image processing: Key considerations for new biological discoveries,” Current Opinion in Structural Biology, vol. 93, p. 103116, 2025. == Abstract == Cryo-electron tomography (cryo-ET) enables 3D visualization of complex biological environments without the need for purification, thereby preserving the native biological context of the specimen. For determining macromolecular structures, repeating..."2025-07-15T06:29:53Z<p>Created page with "== Citation == W. Wan, “A practical look at cryo-electron tomography image processing: Key considerations for new biological discoveries,” Current Opinion in Structural Biology, vol. 93, p. 103116, 2025. == Abstract == Cryo-electron tomography (cryo-ET) enables 3D visualization of complex biological environments without the need for purification, thereby preserving the native biological context of the specimen. For determining macromolecular structures, repeating..."</p>
<p><b>New page</b></p><div>== Citation ==<br />
<br />
W. Wan, “A practical look at cryo-electron tomography image processing: Key considerations for new biological discoveries,” Current Opinion in Structural Biology, vol. 93, p. 103116, 2025.<br />
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== Abstract ==<br />
<br />
Cryo-electron tomography (cryo-ET) enables 3D visualization<br />
of complex biological environments without the need for purification,<br />
thereby preserving the native biological context of the<br />
specimen. For determining macromolecular structures,<br />
repeating molecules can be localized in tomograms and<br />
subjected to subtomogram averaging, the 3D analog to single<br />
particle analysis. In addition to molecular structure, tomograms<br />
have a wealth of other information that can be accessed<br />
through image processing, including the analysis of membrane<br />
surfaces, cytoskeletal filaments, and the relationships between<br />
molecules of interest. Here, we provide an overview of recent<br />
developments in cryo-ET image processing with the goal of<br />
clarifying key considerations to help new users obtain novel<br />
biological findings.<br />
<br />
== Keywords ==<br />
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== Links ==<br />
<br />
https://www.sciencedirect.com/science/article/pii/S0959440X25001344<br />
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== Related software ==<br />
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== Related methods ==<br />
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== Comments ==</div>WikiSysop