Fernández JJ, Li S. Anisotropic nonlinear filtering of cellular structures in cryoelectron tomography. IEEE Computing in Science and Engineering, 7(5):54-61, 2005.
Cryoelectron tomography attempts to allow the visualization of complex biological specimens’ molecular architecture. This technique yields 3D maps with an extremely low signal-to-noise ratio. A new approach based on anisotropic nonlinear diffusion offers a strategy to reduce the noise and enhance local structures.
Electron tomography; Denoising; Anisotropic nonlinear diffusion