2018Scapin DrugDiscovery

Citation

Scapin, G.; Potter, C. S. & Carragher, B. Cryo-EM for Small Molecules Discovery, Design, Understanding, and Application. Cell chemical biology, 2018, 25, 1318-1325

Abstract

We present a perspective of our view of the application of cryoelectron microscopy (cryo-EM) to structure-based drug design (SBDD). We discuss the basic needs and requirements for SBDD, the current state of cryo-EM, and the challenges that need to be overcome for this technique to reach its full potential in facilitating the process of drug discovery.

Links

https://www.sciencedirect.com/science/article/pii/S2451945618302332