2022Subramaniam Comment

Citation

Subramaniam, Sriram / Kleywegt, Gerard J. A paradigm shift in structural biology. 2022-01, Nature methods, Vol. 19, p. 20-23

Abstract

The release of protein structure predictions from AlphaFold will increase the number of protein structural models by almost three orders of magnitude. Structural biology and bioinformatics will never be the same, and the need for incisive experimental approaches will be greater than ever. Combining these advances in structure prediction with recent advances in cryo-electron microscopy suggests a new paradigm for structural biology.

Links

https://www.nature.com/articles/s41592-021-01361-7