User contributions for Vilas

20 February 2026

• 13:1713:17, 20 February 2026 diff hist +2,111 N 2026Liu nextPYP Created page with "== Citation == HF. Liu, Y. Zhou, Q. Huang, et al. In situ structure determination of conformationally flexible targets using nextPYP. Nat Protoc 21, 851–871 (2026). == Abstract == Single-particle cryoelectron tomography (SP-CET) is an imaging technique capable of determining the structure of proteins in their cellular environment at high-resolution. nextPYP is a web-based application designed to streamline the SP-CET structure determination process and facilitate t..." current
• 13:1313:13, 20 February 2026 diff hist +74 Main Page →Subtomogram analysis current
• 12:5812:58, 20 February 2026 diff hist +1,538 N 2026Schreiber Turonova TANGO Created page with "== Citation == M. Schreiber, B. Turoňová, TANGO: Analysis and curation of particles in cryo-electron tomography. Nat Commun 17, 1557 (2026). == Abstract == Cryo-electron tomography (cryo-ET) enables the visualization of cellular structures in near-native environments, but its potential for spatial analysis has been underutilized due to a lack of versatile tools accommodating biological sample diversity. Available solutions often rely on case-specific or hypothesis..." current
• 12:5312:53, 20 February 2026 diff hist +84 Main Page →Subtomogram analysis
• 12:4312:43, 20 February 2026 diff hist +1,484 N 2026JCarrion JDavis insituHet3D Created page with "== Citation == J. Carrion, and J. Davis, "Resolving structural heterogeneity in situ through cryogenic electron tomography", Current Opinion in Structural Biology, Volume 96, 103188, 2026 == Abstract == Cryogenic electron tomography (cryoET) has emerged as a powerful tool for studying the structural heterogeneity of proteins and their complexes, offering insights into macromolecular dynamics directly within cells. Driven by recent computational advances, including pow..." current
• 12:4012:40, 20 February 2026 diff hist +94 Main Page →Subtomogram analysis

29 December 2025

• 14:3914:39, 29 December 2025 diff hist +1,454 N 2025Sharma DataCollection Created page with "== Citation == K. Sharma, M.J. Borgnia, "Advances in automation for cryo-electron tomography data collection", Current Opinion in Structural Biology, Volume 95, 103192, 2025 == Abstract == Cryo-electron microscopy has become the preferred method for determining structures of macromolecular complexes both in isolation, using single particle analysis, and in their cellular contexts, using cryo-electron tomography (Cryo-ET) combined with subvolume averaging (SVA). Collec..." current
• 14:3614:36, 29 December 2025 diff hist +136 Main Page →Electron tomography
• 14:2914:29, 29 December 2025 diff hist +1,389 N 2025Bartesaghi StrategiesHet3D Created page with "== Citation == A. Bartesaghi, "Strategies for studying discrete heterogeneity in situ using cryo-electron tomography", Current Opinion in Structural Biology, Volume 95, 103186, 2025 == Abstract == Structural variability plays a crucial role in enabling biological function, as the ability of proteins to adopt multiple conformations allows them to perform diverse cellular tasks. Cryo-electron tomography combined with subtomogram averaging and classification has emerged..." current
• 14:2514:25, 29 December 2025 diff hist +98 Main Page →Subtomogram analysis

16 October 2025

• 14:4714:47, 16 October 2025 diff hist +1,658 N 2025Roth ArtiaX Created page with "== Citation == P. Roth, U.H. Ermel, D. Moser, G. Arctaedius, M. Wehrheim, M.P. Scheffer, A.S. Frangakis, ArtiaX: geometric models, camera paths and image processing tools, Journal of Structural Biology, 217, 3, 2025. == Abstract == Biomolecular image analysis and data interpretation is significantly improved through the application of advanced visualization techniques. Numerous visualization packages are currently available, spanning a broad spectrum of applications...." current