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• 22:06, 13 August 2025 WikiSysop talk contribs blocked 169.254.2.101 talk with an expiration time of indefinite (anonymous users only, account creation disabled)
• 09:45, 11 August 2025 WikiSysop talk contribs created page User talk:Mikeltxo (Welcome!)
• 09:45, 11 August 2025 WikiSysop talk contribs created page User:Mikeltxo (Creating user page for new user.)
• 09:45, 11 August 2025 User account Mikeltxo talk contribs was created by WikiSysop talk contribs and password was sent by email (Cuenta para Mikel)
• 06:53, 15 July 2025 WikiSysop talk contribs created page 2025Van Probabilistic (Created page with "== Citation == C. T. Van et al., “Probabilistic single-particle cryo-EM ab initio 3D reconstruction in SIMPLE,” Biological Crystallography, vol. 81, no. 8, 2025. == Abstract == Three-dimensional (3D) structure determination by single-particle analysis of cryo-electron microscopy (cryo-EM) images requires ab initio 3D reconstruction of density volume(s) from 2D images (particles). This large-scale inverse problem requires the determination of many million degrees o...")
• 06:42, 15 July 2025 WikiSysop talk contribs created page 2025Zamanos CryoEMMAE (Created page with "== Citation == A. Zamanos, P. Koromilas, G. Bouritsas, P. L. Kastritis, and Y. Panagakis, “Self-supervised learning for generalizable particle picking in cryo-EM micrographs,” Cell Reports Methods, 2025. == Abstract == We present cryoelectron microscopy masked autoencoder (cryo-EMMAE), a self-supervised method designed to overcome the need for manually annotated cryo-EM data. cryo-EMMAE leverages the representation space of a masked autoencoder to pick particle pi...")
• 06:29, 15 July 2025 WikiSysop talk contribs created page 2025Wan Review (Created page with "== Citation == W. Wan, “A practical look at cryo-electron tomography image processing: Key considerations for new biological discoveries,” Current Opinion in Structural Biology, vol. 93, p. 103116, 2025. == Abstract == Cryo-electron tomography (cryo-ET) enables 3D visualization of complex biological environments without the need for purification, thereby preserving the native biological context of the specimen. For determining macromolecular structures, repeating...")
• 07:43, 14 July 2025 WikiSysop talk contribs created page 2025Shub Mic (Created page with "== Citation == L. Shub, W. Liu, G. Skiniotis, M. J. Keiser, and M. J. Robertson, “MIC: A deep learning tool for assigning ions and waters in cryo-EM and crystal structures,” Nature Communications, vol. 16, no. 1, p. 6182, 2025. == Abstract == At sufficiently high resolution, x-ray crystallography and cryogenic electron microscopy are capable of resolving small spherical map features corresponding to either water or ions. Correct classification of these sites provi...")
• 07:54, 11 July 2025 WikiSysop talk contribs created page 2025Wang E3CryoFold (Created page with "== Citation == J. Wang, C. Tan, Z. Gao, G. Zhang, Y. Zhang, and S. Z. Li, “End-to-end Cryo-EM complex structure determination with high accuracy and ultra-fast speed,” Nature Machine Intelligence, pp. 1–13, 2025. == Abstract == While cryogenic-electron microscopy yields high-resolution density maps for complex structures, accurate determination of the corresponding atomic structures still necessitates significant expertise and labour-intensive manual interpretat...")
• 06:34, 10 July 2025 WikiSysop talk contribs created page 2025Chen CryoCRAB (Created page with "== Citation == Q. Chen et al., “A large-scale curated and filterable dataset for cryo-EM foundation model pre-training,” Scientific Data, vol. 12, no. 1, p. 960, 2025. == Abstract == Cryo-electron microscopy (cryo-EM) is a transformative imaging technology that enables near-atomic resolution 3D reconstruction of target biomolecule, playing a critical role in structural biology and drug discovery. Cryo-EM faces significant challenges due to its extremely low signal...")
• 07:13, 8 July 2025 WikiSysop talk contribs created page 2025Gilles Covariance (Created page with "== Citation == M. A. Gilles and A. Singer, “Cryo-EM heterogeneity analysis using regularized covariance estimation and kernel regression,” Proc. Natl. Academy of Sciences, vol. 122, no. 9, p. e2419140122, 2025. == Abstract == Proteins and the complexes they form are central to nearly all cellular processes. Their flexibility, expressed through a continuum of states, provides a window into their biological functions. Cryogenic electron microscopy (cryo-EM) is an id...")
• 07:05, 8 July 2025 WikiSysop talk contribs created page 2025Chaillet PytomMatchPick (Created page with "== Citation == M. L. Chaillet, S. Roet, R. C. Veltkamp, and F. Förster, “pytom-match-pick: a tophat-transform constraint for automated classification in template matching,” J. Structural Biology X, p. 100125, 2025. == Abstract == Template matching (TM) in cryo-electron tomography (cryo-ET) enables in situ detection and localization of known macromolecules. However, TM faces challenges of weak signal of the macromolecules and interfering features with a high signa...")
• 06:54, 8 July 2025 WikiSysop talk contribs created page 2025Bai NUDFT (Created page with "== Citation == Z. Bai and J. Huang, “Non-uniform Fourier transform based image classification in single-particle Cryo-EM,” J. Structural Biology X, p. 100121, 2025. == Abstract == In the single-particle Cryo-EM projection image classification, it is a common practice to apply the Fourier transform to the images and extract rotation-invariant features in the frequency domain. However, this process involves interpolation, which can reduce the accuracy of the results...")
• 06:46, 1 July 2025 WikiSysop talk contribs created page 2025Carr Map2Seq (Created page with "== Citation == K. D. Carr et al., “Protein identification using cryo-EM and artificial intelligence guides improved sample purification,” Journal of Structural Biology: X, p. 100120, 2025. == Abstract == Protein purification is essential in protein biochemistry, structural biology, and protein design, enabling the determination of protein structures, the study of biological mechanisms, and the characterization of both natural and de novo designed proteins. However...")
• 06:40, 1 July 2025 WikiSysop talk contribs created page 2025Wu ZeroLossCCCorrected (Created page with "== Citation == J. Wu et al., “Chromatic aberration (Cc) corrected cryo-EM: the structure of pseudorabies virus (PRV) using both zero-loss and energy loss electrons,” Ultramicroscopy, p. 114182, 2025. == Abstract == Here we have investigated the potential improvement in imaging vitrified biological specimens with the help of a chromatic aberration (Cc)-corrector. Using a newly developed chromatic aberration-corrected electron cryomicroscope (cryo-EM), the phase con...")
• 06:59, 30 June 2025 WikiSysop talk contribs created page 2025Patwardhan Extending (Created page with "== Citation == A. Patwardhan, R. Henderson, and C. J. Russo, “Extending the reach of single-particle cryoEM.,” Current Opinion in Structural Biology, p. 103005, 2025. == Abstract == Molecular structure determination using electron cryomicroscopy (cryoEM) is poised in early 2025 to surpass X-ray crystallography as the most used method for experimentally determining new structures. But the technique has not reached the physical limits set by radiation damage and the...")
• 08:06, 25 June 2025 WikiSysop talk contribs created page 2025Singh Mismatch (Created page with "== Citation == P. K. Singh and T. Iverson, “Improving CryoEM maps of symmetry-mismatched macromolecular assemblies: A case study on the flagellar motor,” J. Structural Biology, vol. 217, no. 2, p. 108184, 2025. == Abstract == Advances in cryo-electron microscopy instrumentation and sample preparation have significantly improved the ability to collect quality data for biomolecular structures. However, achieving resolutions consistent with data quality remains chall...")
• 05:57, 25 June 2025 WikiSysop talk contribs created page 2025Wan CryoETStandards (Created page with "== Citation == W. Wan, “A case for community metadata standards in cryo-electron tomography,” Emerging Topics in Life Sciences, vol. 9, no. 01, p. ETLS20240013, 2025. == Abstract == In the past decade, cryo-electron microscopy and single particle analysis (SPA) have quickly become key methods in structural biology. In particular, increased access to equipment and streamlined software has enabled new users to successfully carry out SPA projects. At the same time, c...")
• 06:32, 24 June 2025 WikiSysop talk contribs created page 2025Riahi EMPOT (Created page with "== Citation == A. Tajmir Riahi, C. Zhang, A. Condon, J. Chen, and K. Dao Duc, “Alignment of Partially Overlapping Cryo-EM Maps Using Unbalanced Gromov-Wasserstein Divergence,” PRX Life, vol. 3, no. 2, p. 23003, 2025. == Abstract == Aligning EM density maps and fitting atomic models are essential steps in single-particle cryogenic electron microscopy (cryo-em), with recent methods leveraging various algorithms and machine learning tools. As aligning maps remains ch...")
• 06:24, 24 June 2025 WikiSysop talk contribs created page 2025Zhan AITom (Created page with "== Citation == X. Zhan, X. Zeng, M. R. Uddin, and M. Xu, “AITom: AI-guided cryo-electron tomography image analyses toolkit,” Journal of Structural Biology, p. 108207, 2025. == Abstract == Cryo-electron tomography (cryo-ET) is an essential tool in structural biology, uniquely capable of visualizing three-dimensional macromolecular complexes within their native cellular environments, thereby providing profound molecular-level insights. Despite its significant promis...")
• 06:19, 24 June 2025 WikiSysop talk contribs created page 2025Zhang Emol (Created page with "== Citation == Z. Zhang, L. Xu, S. Zhang, C. Peng, G. Zhang, and X. Zhou, “EMol: modeling protein-nucleic acid complex structures from cryo-EM maps by coupling chain assembly with map segmentation,” Nucleic Acids Research, p. gkaf416, 2025. == Abstract == Atomic str uct ure modeling is a cr ucial step in determining the str uct ures of protein comple x es using cry o-electron microscop y (cry o-EM). T his work introduces DEMO-EMol, an improved server that integrat...")
• 10:37, 20 June 2025 WikiSysop talk contribs created page 2025Chen GMMs (Created page with "== Citation == M. Chen, “Building molecular model series from heterogeneous CryoEM structures using Gaussian mixture models and deep neural networks,” Communications Biology, vol. 8, no. 1, pp. 1–9, 2025. == Abstract == Cryogenic electron microscopy (CryoEM) produces structures of macromolecules at near-atomic resolution. However, building molecular models with good stereochemical geometry from those structures can be challenging and time-consuming, especially w...")
• 10:30, 20 June 2025 WikiSysop talk contribs created page 2025Guo Alignment (Created page with "== Citation == S. Guo, Z. Xu, X. Li, Z. Yang, C. Feng, and R. Han, “Robust projection parameter calibration in cryo-ET with L1-norm optimization,” Ultramicroscopy, p. 114134, 2025. == Abstract == Fiducial marker-based alignment in cryo-electron tomography (cryo-ET) has been extensively studied over a long period. The calibration of projection parameters using nonlinear least squares technique methodologies stands as the ultimate and pivotal stage in the alignment...")
• 10:26, 20 June 2025 WikiSysop talk contribs created page 2025Martinez Review (Created page with "== Citation == A. Martinez-Sanchez, “Template matching and machine learning for cryo-electron tomography,” Current Opinion in Structural Biology, vol. 93, p. 103058, 2025. == Abstract == Cryo-electron tomography is the best-suited imaging technique for visual proteomics. Recent advances have increased the number, quality, and resolution of tomograms. However, object detection is the bottleneck task of the analysis workflow because, so far, only a few molecules can...")
• 10:13, 20 June 2025 WikiSysop talk contribs created page 2025Khavnekar PSD (Created page with "== Citation == S. Khavnekar and W. Wan, “An approach for coherent periodogram averaging of tilt-series data for improved contrast transfer function estimation,” FEBS Open Bio, 2025. == Abstract == Cryo-electron microscopy (cryo-EM) has become an indispensable technique for determining three-dimensional structures of biological macromolecules. A critical aspect of achieving high-resolution cryo-EM reconstructions is accurately determining and correcting for the mic...")
• 10:05, 20 June 2025 WikiSysop talk contribs created page 2025Kiewisz ProjectionSynthesis (Created page with "== Citation == R. Kiewisz, G. Meyer-Lee, and T. Bepler, “A latent back-projection network for novel projection synthesis for improved Cryo-ET,” in ICLR 2025 Workshop on Generative and Experimental Perspectives for Biomolecular Design, == Abstract == Cryo-electron tomography (Cryo-ET) is hindered by the missing wedge, a gap in Fourier-space information caused by limited tilt-series angular coverage, leading to anisotropic resolution loss and artifacts. Current meth...")
• 09:59, 20 June 2025 WikiSysop talk contribs created page 2025Neiterman Frames (Created page with "== Citation == E. H. Neiterman, A. Heimowitz, and G. Ben-Artzi, “A non-parametric approach to particle picking in all frames,” J. Structural Biology, p. 108201, 2025. == Abstract == Single-particle cryo-electron microscopy (cryo-EM) has significantly advanced macromolecular structure reconstruction. However, a key limitation is the conventional reliance on micrographs obtained by motion correction and averaging, which inherently loses the richness of information c...")
• 09:44, 20 June 2025 WikiSysop talk contribs created page 2025Dickerson Damage (Created page with "== Citation == J. L. Dickerson et al., “Reducing the effects of radiation damage in cryo-EM using liquid helium temperatures,” Proc. Natl. Academy of Sciences, vol. 122, no. 17, p. e2421538122, 2025. == Abstract == The physical limit in determining the atomic structure of biological molecules is radiation damage. In electron cryomicroscopy, there have been numerous attempts to reduce the effects of radiation damage by cooling the specimen beyond liquid-nitrogen te...")
• 09:01, 20 June 2025 WikiSysop talk contribs created page 2025Kinman SIREN (Created page with "== Citation == L. F. Kinman, M. V. Carreira, B. M. Powell, and J. H. Davis, “Automated model-free analysis of cryo-EM volume ensembles with SIREn,” Structure, vol. 33, no. 5, pp. 974–987, 2025. == Abstract == Cryogenic electron microscopy (cryo-EM) has the potential to capture snapshots of proteins in motion and generate hypotheses linking conformational states to biological function. This potential has been increasingly realized by the advent of machine learnin...")
• 05:51, 30 May 2025 WikiSysop talk contribs created page 2025Mallet crAI (Created page with "== Citation == V. Mallet, C. Rapisarda, H. Minoux, and M. Ovsjanikov, “Finding antibodies in cryo-EM maps with CrAI,” Bioinformatics, vol. 41, no. 5, p. btaf157, 2025. == Abstract == Motivation Therapeutic antibodies have emerged as a prominent class of new drugs due to their high specificity and their ability to bind to several protein targets. Once an initial antibody has been identified, its design and characteristics are refined using structural information, w...")
• 06:04, 16 May 2025 WikiSysop talk contribs created page 2024Levy Hydra (Created page with "== Citation == A. Levy et al., “Mixture of neural fields for heterogeneous reconstruction in cryo-EM,” Advances in Neural Information Processing Systems, vol. 37, pp. 56988–57017, 2024. == Abstract == Cryo-electron microscopy (cryo-EM) is an experimental technique for protein structure determination that images an ensemble of macromolecules in near-physiological contexts. While recent advances enable the reconstruction of dynamic conformations of a single biomol...")
• 07:33, 30 April 2025 WikiSysop talk contribs created page 2020Zeng GumNet (Created page with "== Citation == X. Zeng and M. Xu, “Gum-net: Unsupervised geometric matching for fast and accurate 3d subtomogram image alignment and averaging,” in Proc. of the IEEE/CVF Conference on Computer Vision and Pattern Recognition, 2020, pp. 4073–4084. == Abstract == We propose a Geometric unsupervised matching Net- work (Gum-Net) for finding the geometric correspondence between two images with application to 3D subtomogram alignment and averaging. Subtomogram alignmen...")
• 07:12, 23 April 2025 WikiSysop talk contribs created page 2025Harar FakET (Created page with "== Citation == P. Harar, L. Herrmann, P. Grohs, and D. Haselbach, “Faket: Simulating cryo-electron tomograms with neural style transfer,” Structure, vol. 33, no. 4, pp. 820–827, 2025. == Abstract == In cryo-electron microscopy, accurate particle localization and classification are imperative. Recent deep learning solutions, though successful, require extensive training datasets. The protracted generation time of physics-based models, often employed to produce th...")
• 07:00, 21 April 2025 WikiSysop talk contribs created page 2025Schoennenbeck CryoVIA (Created page with "== Citation == P. Schönnenbeck, B. Junglas, and C. Sachse, “CryoVIA: An image analysis toolkit for the quantification of membrane structures from cryo-EM micrographs,” Structure, 2025. == Abstract == Imaging of lipid structures and associated protein complexes using cryoelectron microscopy (cryo-EM) is a common visualization and structure determination technique. The quantitative analysis of the membrane structures, however, is not routine and time consuming in p...")
• 10:43, 16 April 2025 WikiSysop talk contribs created page 2025Woollard InstaMap (Created page with "== Citation == G. Woollard et al., “InstaMap: instant-NGP for cryo-EM density maps,” Biological Crystallography, vol. 81, no. 4, 2025. == Abstract == Despite the parallels between problems in computer vision and cryo-electron microscopy (cryo-EM), many state-of-the-art approaches from computer vision have yet to be adapted for cryo-EM. Within the computer-vision research community, implicits such as neural radiance fields (NeRFs) have enabled the detailed reconstr...")
• 15:28, 15 April 2025 WikiSysop talk contribs created page 2025Kapnulin Outlier (Created page with "== Citation == L. Kapnulin, A. Heimowitz, and N. Sharon, “Outlier removal in cryo-EM via radial profiles,” J. Structural Biology, p. 108172, 2025. == Abstract == The process of particle picking, a crucial step in cryo-electron microscopy (cryo-EM) image analysis, often encounters challenges due to outliers, leading to inaccuracies in downstream processing. In response to this challenge, this research introduces an additional automated step to reduce the number of...")
• 13:58, 15 April 2025 WikiSysop talk contribs created page 2025Chen GCTransNet (Created page with "== Citation == C. Chen, Y. Yan, J. Wu, and W.-B. Gan, “GCTransNet: 3D mitochondrial instance segmentation based on Global Context Vision Transformers,” J. Structural Biology, p. 108170, 2025. == Abstract == Mitochondria are double membrane-bound organelles essential for generating energy in eukaryotic cells. Mitochondria can be readily visualized in 3D using Volume Electron Microscopy (vEM), and accurate image segmentation is vital for quantitative analysis of mit...")
• 13:53, 15 April 2025 WikiSysop talk contribs created page 2025Haynes OptimalIce (Created page with "== Citation == R. M. Haynes, J. Myers, C. S. López, J. Evans, O. Davulcu, and C. Yoshioka, “A strategic approach for efficient cryo-EM grid optimization using design of experiments,” J. Structural Biology, vol. 217, no. 1, p. 108068, 2025. == Abstract == In recent years, cryo-electron microscopy (cryo-EM) has become a practical and effective method of determining structures at previously unattainable resolutions due to advances in detection, automation, and data...")
• 10:29, 14 April 2025 WikiSysop talk contribs created page 2023Shi Compression (Created page with "== Citation == H. Shi, C. Wu, and X. Zhang, “Addressing compressive deformation of proteins embedded in crystalline ice,” Structure, vol. 31, no. 2, pp. 213–220, 2023. == Abstract == For cryoelectron microscopy (cryo-EM), high cooling rates have been required for preparation of protein samples to vitrify the surrounding water and avoid formation of damaging crystalline ice. Whether and how crystalline ice affects single-particle cryo-EM is still unclear. Here, s...")
• 10:00, 14 April 2025 WikiSysop talk contribs created page 2025Bhandari Fast (Created page with "== Citation == J. Bhandari, D. Kompaniiets, A. K. Singh, C. Bator, J. Porta, and B. Liu, “Efficient strategies and troubleshooting for single particle cryoEM data collection using EPU,” BMC Methods, vol. 2, no. 1, p. 3, 2025. == Abstract == Background CryoEM has gained popularity due to advancements in both hardware and software, making it possible to visualize biological molecular structures in detail. However, despite its growing use, cryoEM remains a costly tec...")
• 09:44, 14 April 2025 WikiSysop talk contribs created page 2024Bai NUFT (Created page with "== Citation == Z. Bai and J. Huang, “Non-uniform Fourier transform based image classification in single-particle Cryo-EM,” J. Structural Biology X, p. 100121, 2025. == Abstract == In the single-particle Cryo-EM projection image classification, it is a common practice to apply the Fourier transform to the images and extract rotation-invariant features in the frequency domain. However, this process involves interpolation, which can reduce the accuracy of the results...")
• 09:05, 14 April 2025 WikiSysop talk contribs created page 2008Downing Twin (Created page with "== Citation == K. H. Downing and R. M. Glaeser, “Restoration of weak phase-contrast images recorded with a high degree of defocus: the “twin image” problem associated with CTF correction.,” Ultramicroscopy, vol. 108, no. 9, pp. 921–928, Aug. 2008, doi: 10.1016/j.ultramic.2008.03.004. == Abstract == Relatively large values of objective-lens defocus must normally be used to produce detectable levels of image contrast for unstained biological specimens, which a...")
• 08:57, 14 April 2025 WikiSysop talk contribs created page 2025Zhu Quality (Created page with "== Citation == H. Zhu, G. Terashi, F. Farheen, T. Nakamura, and D. Kihara, “AI-based quality assessment methods for protein structure models from Cryo-EM,” Current Research in Structural Biology, p. 100164, 2025. == Abstract == Cryogenic electron microscopy (cryo-EM) has revolutionized structural biology, with an increasing number of structures being determined by cryo-EM each year, many at higher resolutions. However, challenges remain in accurately interpreting...")
• 08:46, 10 April 2025 WikiSysop talk contribs created page 2025Shah TomoCPT (Created page with "== Citation == P. N. Shah, R. Sanchez-Garcia, and D. I. Stuart, “TomoCPT: a generalizable model for 3D particle detection and localization in cryo-electron tomograms,” Biological Crystallography, vol. 81, pp. 63–76, 2025. == Abstract == Cryo-electron tomography is a rapidly developing field for studying macromolecular complexes in their native environments and has the potential to revolutionize our understanding of protein function. However, fast and accurate id...")
• 08:37, 10 April 2025 WikiSysop talk contribs created page 2025Cao EMInfo (Created page with "== Citation == H. Cao, J. He, T. Li, and S.-Y. Huang, “Deciphering Protein Secondary Structures and Nucleic Acids in Cryo-EM Maps Using Deep Learning,” J. Chemical Information and Modeling, 2025. == Abstract == With the resolution revolution of cryo-electron microscopy (cryo-EM) and the rapid development of image processing technology, cryo-EM has become an indispensable experimental method for determining the three-dimensional structures of biological macromolecu...")
• 11:51, 4 March 2025 WikiSysop talk contribs created page 2025Farheen Modeling (Created page with "== Citation == F. Farheen, G. Terashi, H. Zhu, and D. Kihara, “AI-based methods for biomolecular structure modeling for Cryo-EM,” Current Opinion in Structural Biology, vol. 90, p. 102989, 2025. == Abstract == Cryo-electronmicroscopy (Cryo-EM) has revolutionized structural biology by enabling the determination of macromolecular structures that were challenging to study with conventional methods. Processing cryo-EM data involves several computational steps to deriv...")
• 07:43, 19 February 2025 WikiSysop talk contribs created page 2025Liu SpIsonet (Created page with "== Citation == Y.-T. Liu, H. Fan, J. J. Hu, and Z. H. Zhou, “Overcoming the preferred orientation problem in cryoEM with self-supervised deep-learning,” Nature methods, vol. 22, pp. 113–123, 2025. == Abstract == While advances in single-particle cryo-EM have enabled the structural determination of macromolecular complexes at atomic resolution, particle orientation bias (the ‘preferred’ orientation problem) remains a complication for most specimens. Existing...")
• 09:15, 18 February 2025 WikiSysop talk contribs created page 2024Tang SimCryoCluster (Created page with "== Citation == H. Tang, Y. Wang, J. Ouyang, and J. Wang, “Simcryocluster: a semantic similarity clustering method of cryo-EM images by adopting contrastive learning,” BMC bioinformatics, vol. 25, no. 1, p. 77, 2024. == Abstract == Background: Cryo-electron microscopy (Cryo-EM) plays an increasingly important role in the determination of the three-dimensional (3D) structure of macromolecules. In order to achieve 3D reconstruction results close to atomic resolution,...")
• 09:04, 18 February 2025 WikiSysop talk contribs created page 2024Li CryoStar (Created page with "== Citation == Y. Li, Y. Zhou, J. Yuan, F. Ye, and Q. Gu, “CryoSTAR: leveraging structural priors and constraints for cryo-EM heterogeneous reconstruction,” Nature Methods, pp. 1–9, 2024. == Abstract == Resolving conformational heterogeneity in cryogenic electron microscopy datasets remains an important challenge in structural biology. Previous methods have often been restricted to working exclusively on volumetric densities, neglecting the potential of incorpor...")
• 14:27, 11 February 2025 WikiSysop talk contribs created page 2025Yan MPicker (Created page with "== Citation == X. Yan et al., “MPicker: visualizing and picking membrane proteins for cryo-electron tomography,” Nature Communications, vol. 16, no. 1, p. 472, 2025. == Abstract == Advancements in cryo-electron tomography (cryoET) allow the structure of macromolecules to be determined in situ, which is crucial for studying membrane protein structures and their interactions in the cellular environment. However, membranes are often highly curved and have a strong co...")