Main public logs

Combined display of all available logs of 3DEM-Methods. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).

• 08:14, 7 January 2026 WikiSysop talk contribs created page 2026Mulvaney CASP16 (Created page with "== Citation == Mulvaney, T., Kryshtafovych, A. and Topf, M. 2026. Cryo-EM Analysis in CASP16. Proteins: Structure, Function, and Bioinformatics. (2026). == Abstract == Since CASP13, experimentalists have been encouraged to provide their cryo-EM data along with the derived atomic models to the CASP organizers to aid assessment. In CASP16, 38 cryo-EM datasets were provided for assessment, which represented most cryo-EM targets. The corresponding targets typically compri...")
• 08:06, 7 January 2026 WikiSysop talk contribs created page 2025Tang CryoLike (Created page with "== Citation == Tang, W.S., Soules, J., Rangan, A. and Cossio, P. 2025. CryoLike: a Python package for cryo-electron microscopy image-to-structure likelihood calculations. Biological Crystallography. 81, 12 (2025). == Abstract == Extracting conformational heterogeneity from cryo-electron microscopy (cryo-EM) images is particularly challenging for flexible biomolecules, where traditional 3D classification approaches often fail. Over the past few decades, advancements in...")
• 09:25, 30 December 2025 WikiSysop talk contribs created page 2025Li EMProt (Created page with "== Citation == Li, T., Chen, J., Li, H., Cao, H. and Huang, S.-Y. 2025. EMProt improves structure determination from cryo-EM maps. Nature Structural & Molecular Biology. (2025), 1–10. == Abstract == Cryo-electron microscopy (cryo-EM) has become the mainstream technique for macromolecular structure determination. However, because of intrinsic resolution heterogeneity, accurate modeling of all-atom structure from cryo-EM maps remains challenging even for maps at near-...")
• 08:48, 30 December 2025 WikiSysop talk contribs created page 2025Leone Review (Created page with "== Citation == Leone, V. and Marinelli, F. 2025. From snapshots to ensembles: Integrating experimental data and dynamics. Current Opinion in Structural Biology. 95, (2025), 103155. == Abstract == Protein function arises from the interplay of structure, dynamics, and biomolecular interactions. Despite advances in cryo-EM and AI-based structure prediction, capturing dynamic and energetic features remains a challenge. Biophysical methods like NMR, EPR, HDX-MS, SAXS, and...")
• 14:39, 29 December 2025 Vilas talk contribs created page 2025Sharma DataCollection (Created page with "== Citation == K. Sharma, M.J. Borgnia, "Advances in automation for cryo-electron tomography data collection", Current Opinion in Structural Biology, Volume 95, 103192, 2025 == Abstract == Cryo-electron microscopy has become the preferred method for determining structures of macromolecular complexes both in isolation, using single particle analysis, and in their cellular contexts, using cryo-electron tomography (Cryo-ET) combined with subvolume averaging (SVA). Collec...")
• 14:29, 29 December 2025 Vilas talk contribs created page 2025Bartesaghi StrategiesHet3D (Created page with "== Citation == A. Bartesaghi, "Strategies for studying discrete heterogeneity in situ using cryo-electron tomography", Current Opinion in Structural Biology, Volume 95, 103186, 2025 == Abstract == Structural variability plays a crucial role in enabling biological function, as the ability of proteins to adopt multiple conformations allows them to perform diverse cellular tasks. Cryo-electron tomography combined with subtomogram averaging and classification has emerged...")
• 09:29, 29 December 2025 WikiSysop talk contribs created page 2025Peng DiamTR (Created page with "== Citation == Peng, R., Elkhaligy, H., Grant, T. and Stagg, S.M. 2025. DiameTR: A cryo-EM tool for diameter sorting of tubular samples. J. Structural Biology: X. (2025), 100136. == Abstract == Tubular structures are ubiquitous in biological systems and have been a focal point of cryo-electron microscopy (cryo-EM) structural analysis since the technique’s inception. A critical step in processing tubular cryo-EM data is particle classification by diameter, as uniform...")
• 09:02, 29 December 2025 WikiSysop talk contribs created page 2025Chen CryoEvoBuilding (Created page with "== Citation == Chen, J., Li, T., He, J. and Huang, S.-Y. 2025. Protein model building for intermediate-resolution cryo-EM maps by integrating evolutionary and experimental information. Structure. (2025). == Abstract == Accurate model building in intermediate-resolution cryo-EM maps normally requires flexible fitting of reliable initial structures. However, while deep learning-based methods such as AlphaFold2 can predict highly accurate structures, the predicted struct...")
• 08:50, 29 December 2025 WikiSysop talk contribs created page 2025Chen Asymmetric (Created page with "== Citation == Chen, W., Zheng, J., Zhou, J., Cheng, L. and Liu, H. 2025. A data-processing strategy of asymmetric reconstruction for tailed phages by Cryo-electron Microscopy. J. Structural Biology. (2025), 108262. == Abstract == The structure of the tailed phage is composed of an icosahedral (or elongated icosahedral) head and a spiral symmetrical tail, which are connected by a portal located at a unique vertex of the icosahedron. A series of image-processing method...")
• 08:33, 22 December 2025 WikiSysop talk contribs created page 2025Li Helicon (Created page with "== Citation == Li, D., Zhang, X. and Jiang, W. 2025. Helicon: Helical parameter determination and 3D reconstruction from one image. J. Structural Biology. (2025), 108256. == Abstract == Helical symmetry is a common structural feature of many biological macromolecules. However, determination of the helical parameters and de novo 3D reconstruction remain challenging. We have developed a computational method, Helicon, which poses helical reconstruction as a linear regres...")
• 15:22, 16 December 2025 WikiSysop talk contribs created page 2025Kim Review (Created page with "== Citation == Kim, H.-u., An, M.Y., Kim, Y.K., Chung, J.M. and Jung, H.S. 2025. Combining Cryo-EM with Computational Approaches To Revolutionize Structural Biology. The Protein Journal. (2025), 1–16. == Abstract == The development of cryo-electron microscopy (cryo-EM) has led to significant advancements in the field of structural biology. Specifically, improvements in both hardware and software for cryo-EM have not only addressed previously perceived limitations bu...")
• 11:14, 21 November 2025 WikiSysop talk contribs created page 2025Su CryoAtom (Created page with "== Citation == Su, B., Huang, K., Peng, Z., Amunts, A. and Yang, J. 2025. CryoAtom improves model building for cryo-EM. Nature Structural & Molecular Biology. (2025), 1–11. == Abstract == Constructing atomic models from cryogenic electron microscopy (cryo-EM) density maps is essential for interpreting molecular mechanisms. Here we present CryoAtom, an approach for de novo model building for cryo-EM maps, leveraging recent advancements in AlphaFold2 to improve the st...")
• 11:07, 21 November 2025 WikiSysop talk contribs created page 2025Fu T2Relion (Created page with "== Citation == Fu, J., Xu, J., Gan, L., Mao, T., Shen, Z., Wang, Y., Song, Z., Duan, X., Xue, W. and Yang, G. 2025. T2-RELION: Task Parallelism, Tensor Core Accelerated RELION for Cryo-EM 3D Reconstruction. Proceedings of the International Conference for High Performance Computing, Networking, Storage and Analysis (2025), 2186–2202. == Abstract == Cryo-electron microscopy (cryo-EM) is a key technique for structural biology, but its computational efficiency, particul...")
• 17:24, 14 November 2025 WikiSysop talk contribs created page 2024Shekarforoush CryoSPIN (Created page with "== Citation == Shekarforoush, S., Lindell, D.B., Brubaker, M.A. and Fleet, D.J. 2024. Cryospin: improving ab-initio cryo-EM reconstruction with semi-amortized pose inference. Advances in Neural Information Processing Systems. 37, (2024), 55785–55809. == Abstract == Cryo-EM is an increasingly popular method for determining the atomic resolution 3D structure of macromolecular complexes (eg, proteins) from noisy 2D images captured by an electron microscope. The computa...")
• 17:03, 14 November 2025 WikiSysop talk contribs created page 2024Wang CommonLines (Created page with "== Citation == Wang, X., Jin, Q., Zou, L., Lin, X. and Lu, Y. 2024. Orientation Determination of Cryo-EM Projection Images Using Reliable Common Lines and Spherical Embeddings. IEEE/ACM Transactions on Computational Biology and Bioinformatics. (2024). == Abstract == Three-dimensional (3D) reconstruction in singleparticle cryo-electronmicroscopy (cryo-EM) is a critical technique for recovering and studying the fine 3D structure of proteins and other biological macromol...")
• 09:21, 13 November 2025 WikiSysop talk contribs created page 2025Chen GMM (Created page with "== Citation == Chen, M. 2025. Building molecular model series from heterogeneous CryoEM structures using Gaussian mixture models and deep neural networks. Communications Biology. 8, 1 (2025), 798. == Abstract == Cryogenic electron microscopy (CryoEM) produces structures of macromolecules at near-atomic resolution. However, building molecular models with good stereochemical geometry from those structures can be challenging and time-consuming, especially when many struc...")
• 09:07, 13 November 2025 WikiSysop talk contribs created page 2025Selvaraj CryoTEN (Created page with "== Citation == Selvaraj, J., Wang, L. and Cheng, J. 2025. CryoTEN: efficiently enhancing cryo-EM density maps using transformers. Bioinformatics. 41, 3 (2025), btaf092. == Abstract == Motivation: Cryogenic Electron Microscopy (cryo-EM) is a core experimental technique used to determine the structure of macromolecules such as proteins. However, the effectiveness of cryo-EM is often hindered by the noise and missing density values in cryo-EM density maps caused by exper...")
• 08:37, 13 November 2025 WikiSysop talk contribs created page 2025Bromberg Hand (Created page with "== Citation == Bromberg, R., Guo, Y., Borek, D. and Otwinowski, Z. 2025. Validation of 3D cryoEM single-particle reconstruction correctness and handedness with Ewald’s sphere correction. Structural Dynamics. 12, 5 (2025). == Abstract == The correct description of quantum scattering places the observed scattering contributions on the Ewald's sphere and its Friedel mate copy. In electron microscopy, due to the large radius of the Ewald's sphere, these scattering contr...")
• 17:32, 12 November 2025 WikiSysop talk contribs created page 2025Dhakal Benchmark (Created page with "== Citation == Dhakal, A., Gyawali, R., Wang, L. and Cheng, J. 2025. Artificial intelligence in cryo-EM protein particle picking: recent advances and remaining challenges. Briefings in Bioinformatics. 26, 1 (2025), bbaf011. == Abstract == Cryo-electron microscopy (cryo-EM) has revolutionized structural biology by enabling the determination of high-resolution 3-Dimensional (3D) structures of large biological macromolecules. Protein particle picking, the process of iden...")
• 16:53, 12 November 2025 WikiSysop talk contribs created page 2025Urzhumtsev RescaleFSC (Created page with "== Citation == Urzhumtsev, A.G. 2025. Rescaling FSC curves. Acta Crystallographica Sec. D. 81, 11 (2025). == Abstract == Similarity between two periodic functions is commonly assessed by comparing their Fourier coefficients within resolution shells. In particular, this approach is widely used in both crystallography and cryo-electron microscopy (cryoEM). The definition of these shells, that is the choice of resolution scale for their boundaries, can be guided by the s...")
• 16:33, 12 November 2025 WikiSysop talk contribs created page 2025Morales Membranes (Created page with "== Citation == Morales-Martı́nez, A., Garduño, E., Carazo, J.M., Sorzano, C.O.S. and Vilas, J.L. 2025. Membrane and vesicle structure detection in cryo-electron tomography based on deep learning. J. Structural Biology. (2025), 108258. == Abstract == Cryo-electron tomography (cryo-ET) is a microscopy technique that enables the acquisition of 3D images of biological samples. Research in cell biology has shown that cellular processes are carried out by groups of macro...")
• 14:04, 6 November 2025 WikiSysop talk contribs created page 2025Gusach Diffusion (Created page with "== Citation == Gusach, A., Sader, K. and Russo, C.J. 2025. Outrunning protein diffusion to the air–water interface in cryoEM. Proceedings of the National Academy of Sciences. 122, 43 (2025), e2516900122. == Abstract == Here, we report a series of measurements indicating that it is physically possible to thin and vitrify a specimen for electron cryomicroscopy (cryoEM) faster than proteins diffuse to the air–water interface. We achieved this by spraying picoliter vo...")
• 23:31, 5 November 2025 WikiSysop talk contribs created page 2025Ni GTPick (Created page with "== Citation == Ni, S., Yang, C., Liu, Y., Zhang, Y., Shi, Y., Qian, A., Kong, R. and Chang, S. 2025. GTpick: A Deep Neural Network for Cryo-EM Particle Detection. Computational and Structural Biotechnology Journal. (2025). == Abstract == Accurate identification of protein particles in cryo-electron microscopy (Cryo-EM) images is crucial for achieving high-resolution three-dimensional (3D) structural reconstruction. However, this task faces multiple challenges, includi...")
• 22:43, 2 November 2025 WikiSysop talk contribs created page 2025Elad Review (Created page with "== Citation == Elad, S.T., Ben-Asher, N. and Engel, L. 2025. Cool and collected: Advances in sample preparation for cryo-electron microscopy. Current Opinion in Structural Biology. 94, (2025), 103132. == Abstract == Cryo-electron microscopy (cryo-EM) has emerged as a transformative tool in structural biology, enabling highresolution visualization of macromolecules in their native states. Cryo-focused ion beam milling (cryo-FIB) and other advances in sample preparation...")
• 22:26, 2 November 2025 WikiSysop talk contribs created page 2025Muenks EmeraldID (Created page with "== Citation == Muenks, A., Farrell, D.P., Zhou, G. and DiMaio, F. 2025. Automated identification of small molecules in cryoelectron microscopy data with density-and energy-guided evaluation. Structure. 33, 10 (2025), 1760–1770. == Abstract == Methodological improvements in cryoelectron microscopy (cryo-EM) have made it useful in ligandbound structure determination for biology and drug design. However, determining ligand conformation and identity is challenging at th...")
• 21:35, 2 November 2025 WikiSysop talk contribs created page 2025Li validation (Created page with "== Citation == Li, D., Perez, M.M., Zhang, X., Li, J. and Jiang, W. 2025. Validation of helical symmetry parameters in EMDB. Acta Crystallographica Sec. D. 81, (2025), 527–534. == Abstract == Helical symmetry is a structural feature of many biological assemblies, including cytoskeletons, viruses and pathological amyloid fibrils. The helical parameters twist and rise are unique metadata for helical structures. With the increasing number of helical structures being re...")
• 21:28, 2 November 2025 WikiSysop talk contribs created page 2025Lauzirika Distinguishable (Created page with "== Citation == Lauzirika, O., Pernica, M., Herreros, D., Ramı́rez-Aportela, E., Krieger, J., Gragera, M., Iceta, M., Conesa, P., Fonseca, Y., Jiménez, J., Flipovic, J., Carazo, J.M. and Sorzano, C.O.S. 2025. How many (distinguishable) classes can we identify in single-particle analysis? Acta Crystallographica Sec. D. 81, 10 (2025). == Abstract == Heterogeneity in cryoEM is essential for capturing the structural variability of macromolecules, reflecting their functi...")
• 21:10, 2 November 2025 WikiSysop talk contribs created page 2025Luo DiffFit (Created page with "== Citation == Luo, D., Alsuwaykit, Z., Khan, D., Strnad, O., Isenberg, T. and Viola, I. 2025. DiffFit: Visually-Guided Differentiable Fitting of Molecule Structures to a Cryo-EM Map. IEEE Trans. on Visualization and Computer Graphics. 31, 1 (2025), 558–568. == Abstract == We introduce DiffFit, a differentiable algorithm for fitting protein atomistic structures into an experimental reconstructed Cryo-Electron Microscopy (cryo-EM) volume map. In structural biology, t...")
• 14:47, 16 October 2025 Vilas talk contribs created page 2025Roth ArtiaX (Created page with "== Citation == P. Roth, U.H. Ermel, D. Moser, G. Arctaedius, M. Wehrheim, M.P. Scheffer, A.S. Frangakis, ArtiaX: geometric models, camera paths and image processing tools, Journal of Structural Biology, 217, 3, 2025. == Abstract == Biomolecular image analysis and data interpretation is significantly improved through the application of advanced visualization techniques. Numerous visualization packages are currently available, spanning a broad spectrum of applications....")
• 12:45, 16 October 2025 WikiSysop talk contribs created page 2025Chen Detergent (Created page with "== Citation == Chen, B., Harrison, P., Kargas, V., Pollock, N., Ford, R.C., Prince, S.M. and Collins, R.F. 2025. Coming Clean and Avoiding Bubble Trouble–Using Detergents Wisely in the Purification of Membrane Proteins for Cryo-EM Studies. Biomolecules. 15, 9 (2025), 1315. == Abstract == Detergent solubilisation remains the most commonly used but potentially problematic method to extract membrane proteins from lipid bilayers for Cryo-EM studies. Although recent adva...")
• 16:31, 29 September 2025 WikiSysop talk contribs created page 2025Chung CRISP (Created page with "== Citation == Chung, S.-C. and Chou, P.-C. 2025. CRISP: A modular platform for cryo-EM image segmentation and processing with Conditional Random Field. J. Structural Biology. (2025), 108239. == Abstract == Distinguishing signal from background in cryogenic electron microscopy (cryo-EM) micrographs is a critical processing step but remains challenging owing to the inherently low signal-to-noise ratio (SNR), contaminants, variable ice thickness, and densely packed part...")
• 06:14, 25 September 2025 WikiSysop talk contribs created page 2020Ma RotationInvariant (Created page with "== Citation == Ma, C., Bendory, T., Boumal, N., Sigworth, F. and Singer, A. 2020. Heterogeneous multireference alignment for images with application to 2D classification in single particle reconstruction. IEEE Transactions on Image Processing. 29, (2020), 1699–1710. == Abstract == Motivated by the task of 2D classification in single particle reconstruction by cryo-electron microscopy (cryo-EM), we consider the problem of heterogeneous multireference alignment of ima...")
• 05:56, 25 September 2025 WikiSysop talk contribs created page 2023Cesa Alignment (Created page with "== Citation == Cesa, G., Pratik, K. and Behboodi, A. 2023. Equivariant self-supervised deep pose estimation for Cryo EM. Topological, Algebraic and Geometric Learning Workshops 2023 (2023), 21–36. == Abstract == Reconstructing the 3D volume of a molecule from its differently oriented 2D projections is the central problem of Cryogenic Electron Microscopy (cryo-EM), one of the main techniques for macro-molecule imaging. Because the orientations are unknown, the estima...")
• 16:23, 22 September 2025 WikiSysop talk contribs created page 2025Matsuoka ForceConstant (Created page with "== Citation == Matsuoka, D., Sugita, Y. and Mori, T. 2025. An Empirical Biasing Force Constant to Minimize Overfitting in Cryo-EM Flexible Fitting Refinement. J. Chemical Information and Modelling. (2025). == Abstract == Reliable modeling of protein structures from a cryo- EM density map is one of the central issues in structural biology. Typically, the constructed model is refined using a flexible fitting method combined with molecular dynamics, where a biasing poten...")
• 06:07, 17 September 2025 WikiSysop talk contribs created page User talk:Vilas (Welcome!)
• 06:07, 17 September 2025 WikiSysop talk contribs created page User:Vilas (Creating user page for new user.)
• 06:07, 17 September 2025 User account Vilas talk contribs was created by WikiSysop talk contribs and password was sent by email (One more editor)
• 07:47, 11 September 2025 WikiSysop talk contribs created page 2025Khoshbin Magellon (Created page with "== Citation == Khoshbin, B., Damodar, P., Garje, R.R., Schotanus, F.H., Nair, N., Wei, L., Schaefer, J.-H., Lander, G.C., Cianfrocco, M.A. and Stagg, S.M. 2025. Magellon-an extensible platform for cryo-EM data visualization, management, and processing. IUCrJ. 12, (2025), eh5023. == Abstract == Single-particle cryo-electron microscopy (cryo-EM) has revolutionized structural biology by enabling high-resolution determination of macromolecular structures. However, the fie...")
• 07:35, 11 September 2025 WikiSysop talk contribs created page 2025 Huang (Created page with "== Citation == Huang, M., Ma, J., Fu, X., Wang, H., Shen, Y. and Li, X. 2025. Accurate helical parameter estimation based on cylindrical unrolling. Structure. (2025). == Abstract == Helical structure is fundamental for filamentous and tubular macromolecular assemblies that play crucial roles in structural scaffolding and signaling processes. Structure determination of these assemblies relies on the precise estimation of their helical parameters. Although layer-line-ba...")
• 07:27, 11 September 2025 WikiSysop talk contribs created page 2025Zheng Disorder (Created page with "== Citation == Zheng, S. 2025. Exploring the Bottleneck in Cryo-EM Dynamic Disorder Feature and Advanced Hybrid Prediction Model. Biophysica. 5, 3 (2025), 39. == Abstract == Cryo-electron microscopy single-particle analysis (cryo-EM SPA) has advanced threedimensional protein structure determination, yet resolving intrinsically disordered proteins and regions (IDPs/IDRs) remains challenging due to conformational heterogeneity. This research evaluates cryo-EM’s capaci...")
• 09:32, 29 August 2025 WikiSysop talk contribs created page 2025Karolczak Ligand (Created page with "== Citation == Karolczak, J., Przybyłowska, A., Szewczyk, K., Taisner, W., Heumann, J.M., Stowell, M.H., Nowicki, M. and Brzezinski, D. 2025. Ligand identification in CryoEM and X-ray maps using deep learning. Bioinformatics. 41, 1 (2025), btae749. == Abstract == Motivation: Accurately identifying ligands plays a crucial role in the process of structure-guided drug design. Based on density maps from X-ray diffraction or cryogenic-sample electron microscopy (cryoEM),...")
• 08:44, 29 August 2025 WikiSysop talk contribs created page 2024Jeon CryoBench (Created page with "== Citation == Jeon, M., Raghu, R., Astore, M., Woollard, G., Feathers, J., Kaz, A., Hanson, S., Cossio, P. and Zhong, E. 2024. CryoBench: Diverse and challenging datasets for the heterogeneity problem in cryo-EM. Advances in Neural Information Processing Systems. 37, (2024), 89468–89512. == Abstract == Cryo-electron microscopy (cryo-EM) is a powerful technique for determining high-resolution 3D biomolecular structures from imaging data. Its unique ability to captur...")
• 08:39, 29 August 2025 WikiSysop talk contribs created page 2024Bobe Calibration (Created page with "== Citation == Bobe, D., Kopylov, M., Miller, J., Owji, A.P. and Eng, E.T. 2024. Multi-species cryoEM calibration and workflow verification standard. Structural Biology and Crystallization Communications. 80, 11 (2024), 320–327. == Abstract == Cryogenic electron microscopy (cryoEM) is a rapidly growing structural biology modality that has been successful in revealing molecular details of biological systems. However, unlike established biophysical and analytical tech...")
• 08:07, 29 August 2025 WikiSysop talk contribs created page 2025Haloi Ligand (Created page with "== Citation == Haloi, N., Howard, R.J. and Lindahl, E. 2025. Cryo-EM ligand building using AlphaFold3-like model and molecular dynamics. PLOS Computational Biology. 21, 8 (2025), e1013367. == Abstract == Resolving protein-ligand interactions in atomic detail is key to understanding how small molecules regulate macromolecular function. Although recent breakthroughs in cryogenic electron microscopy (cryo-EM) have enabled high-quality reconstruction of numerous complex b...")
• 07:58, 29 August 2025 WikiSysop talk contribs created page 2025Dingeldein (Created page with "== Citation == Dingeldein, L., Silva-Sánchez, D., Evans, L., D’Imprima, E., Grigorieff, N., Covino, R. and Cossio, P. 2025. Amortized template matching of molecular conformations from cryoelectron microscopy images using simulation-based inference. Proceedings of the National Academy of Sciences. 122, 23 (2025), e2420158122. == Abstract == Characterizing the conformational ensemble of biomolecular systems is key to understand their functions. Cryoelectron microscop...")
• 09:57, 28 August 2025 WikiSysop talk contribs created page 2025Grant Nanodisc (Created page with "== Citation == Grant, A.J. and Schmidt-Krey, I. 2025. Nanodisc-reconstitution for single particle cryo-EM structure determination of membrane proteins. Current Opinion in Structural Biology. 93, (2025), 103072. == Abstract == Reconstitution of membrane proteins in nanodiscs has proven to be a highly effective approach to study membrane protein structures in a lipid bilayer, resulting in many recent single particle cryo-EM structures. While most of these studies employ...")
• 09:43, 28 August 2025 WikiSysop talk contribs created page 2025Herreros HetSiren (Created page with "== Citation == Herreros, D., Mata, C.P., Noddings, C., Irene, D., Krieger, J., Agard, D.A., Tsai, M.-D., Sorzano, C.O.S. and Carazo, J.M. 2025. Real-space heterogeneous reconstruction, refinement, and disentanglement of CryoEM conformational states with HetSIREN. Nature communications. 16, 1 (2025), 3751. == Abstract == Single-particle analysis by Cryo-electron microscopy (CryoEM) provides direct access to the conformations of macromolecules. Traditional methods assum...")
• 10:17, 27 August 2025 WikiSysop talk contribs created page 2025Zhang Benchmark (Created page with "== Citation == Zhang, C., Condon, A. and Dao Duc, K. 2025. A comprehensive survey and benchmark of deep learning-based methods for atomic model building from cryo-electron microscopy density maps. Briefings in Bioinformatics. 26, 4 (2025), bbaf322. == Abstract == Advancements in deep learning (DL) have recently led to new methods for automated construction of atomic models of proteins, from single-particle cryogenic electron microscopy (cryo-EM) density maps. We condu...")
• 08:12, 25 August 2025 WikiSysop talk contribs created page 2025Levy CryoDRGNAI (Created page with "== Citation == Levy, A., Raghu, R., Feathers, J.R., Grzadkowski, M., Poitevin, F., Johnston, J.D., Vallese, F., Clarke, O.B., Wetzstein, G. and Zhong, E.D. 2025. CryoDRGN-AI: neural ab initio reconstruction of challenging cryo-EM and cryo-ET datasets. Nature Methods. (2025), 1–9. == Abstract == Proteins and other biomolecules form dynamic macromolecular machines that are tightly orchestrated to move, bind and perform chemistry. Cryo-electron microscopy and cryo-elec...")
• 09:11, 21 August 2025 WikiSysop talk contribs unblocked 169.254.2.101 talk